CAS: 523-50-2; 2H-Furo[2,3-H]Chromen-2-One

该化合物是天然的化合物,被归类为呋喃,主要来自阿皮塞亚家族的植物,如Angelica archerlica,该化合物的特点是独特的化学结构,包括一个被粘结到豆浆状的松树环,它具有独特的化学结构,它包括一个与豆浆状晶状固体结合的松香环,它展示了一系列的生物活动,包括光毒性,这意味着它可能在接触紫外线时引起皮肤反应.此外,它还研究其潜在的抗癌特性,因为它可能抑制某些癌症细胞的生长.该物质在传统草药中的作用也众所周知,因为在那里,它被用于各种治疗目的.从物理特性来看,天使通常没有色色,不会染色黄色晶状固体,它溶剂在水中溶解,但溶解性有限.它具有再活性和与生物系统的互动性,因此它成为药理学研究的对象.

结构式图片

相似化合物

66-97-7 91-64-5 2009-24-7

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号233-28-3 (2H)-furo[2,3-h... | CAS号112183-09-2 3-phenylsulfany... | CAS号112183-05-8 6-[(trifluorome... | CAS号1361944-38-8 4-benzofuranyl ... | CAS号112183-08-1 3-(phenylthio)-... | CAS号16851-02-8 2-(2-ox°Chromen...

合成工艺路线路线简述

  • 226886-40-4 = 523-50-2 + 905954-18-9
    反应条件:1.1 Solvents: Dimethyl Sulfoxide; 2 H,Rt
    标题:First Total Synthesis Of Isopsoralenoside
    作者:Wu,Min; Xu,Lijia; Song,Mingwei; Li,Ying; Wang,Yingying; Et Al
    参考文献:Letters In Organic Chemistry 日期:2022 卷标:19(10) 页码:832-836
(2H)-Furo<2,3-H>-1-Benzopyran 反应生成 异补骨脂素
参考文献:Wulff,William D.;Mccallum,J. Stuart;Kunng,Fen-Ann,J. Amer: Chem. Soc.,110,(1988) N2,C. 7419-7434
标题:Wulff,William D.;Mccallum,J. Stuart;Kunng,Fen-Ann,J. Amer: Chem. Soc.,110,(1988) N2,C. 7419-7434

海关参考信息

专利信息


专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人:ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.

专利号:US-2021284618-A1
优先权日:2016-08-12
标 题 :Furanochalcones as inhibitors of cyp1a1, cyp1a2 and cyp1b1 for cancer chemoprevention
发明人:BHARATE SANDIP BIBISHAN; SHARMA RAJNI; JOSHI PRASHANT; VISHWAKARMA RAM; CHAUDHURI BHABATOSH
权利人:COUNCIL SCIENT IND RES; DE MONTFORT UNIV
摘要:The present invention relates to the furanochalcone class of compounds of general formula A. The present invention particularly relates to the synthesis of furanochalcones and their CYP1A1, CYP1A2 and CYP1B1 inhibitory activity. In addition, the invention relates to the prevention or treatment of cancer caused by polyaromatic hydrocarbons (PAHs), 4-nitroquinoline-1-oxide, and N-nitroso-N-methylurea, heterocyclic amines, estrogen and 17β-estradiol, resulting from the inhibition of CYP1A1, CYP1A2 and CYP1B1 enzymes.

专利号:US-4230624-A
优先权日:1977-09-02
标 题 :Process for the synthesis of derivatives of the benzofuran, chromene and isochromene type
发明人:LE CORRE MAURICE; HERCOUET ALAIN; BEGASSE BEATRICE
权利人:ANVAR
摘要:The invention relates to a process for the production of therapeutic compounds of the benzofuran, chromene and isochromene type of the general formula; in which formula, R1 and R3=H, lower alkyl, aralkyl or cycloalkyl R2=H or an organic radical and when D= R1 and R3 may represent an organic radical. The process comprising the cyclization in the liquid phase and in the presence of a base a compound of the formula; in which formula; R'=an alkyl, aryl or aralkyl radical and X-=an anion.

专利号:EP-0497921-B1
优先权日:1989-10-26
标 题:Method for inhibiting enzymatic synthesis of nucleic acids using isopsoralens
发明人:ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W; HEARST JOHN E
权利人:ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W; HEARST JOHN E
摘要:The invention relates to a device, comprising means for providing electromagnetic radiation (101-106; 201-206; 301-308); means for supporting a sample (109;315) in a fixed relationship with said radiation providing means during irradiation; a housing (100;200;300) for containing said radiation providing means; and means for maintaining the temperature of said sample within a desired temperature range during said irradiation comprising a chamber (107;207;309) positioned interior to said housing and in a fixed relationship to said radiation providing means.

专利号:US-6962906-B2
优先权日:2000-03-14
标题 :Oligonucleotide analogues, methods of synthesis and methods of use
发明人:EFIMOV VLADIMIR; FERNANDEZ JOSEPH; ARCHDEACON DOROTHY; ARCHDEACON JOHN; CHAKHMAKHCHEVA OKSANA; BURYAKOVA ALLA; CHOOB MIKHAIL; HONDORP KYLE
权利人:ACTIVE MOTIF
摘要:The present invention relates generally to oligonucleotide analogues that include novel protein nucleic acid molecules (PNAs), particularly monomers, dimers, oligomers thereof and methods of making and using these oligonucleotide analogues. The PNAs of the present invention are characterized as including a variety of classes of molecules, such as, for example, hydroxyproline peptide nucleic acids (HypNA), and serine peptide nucleic acids (SerNA). The invention includes monomers, homodimers, heterodimers, homopolymers and heteropolymers of these and other oligonucleotide analogues. The present invention includes methods of using these oligonucleotide analogues in the detection and separating of nucleic acid molecules, including uses that include the utilization of oligonucleotide analogues on a solid support. The present invention also includes methods for purifying or separating nucleic acids, such as mRNA molecules, by hybridization with the oligonucleotides of the present invention. The present invention also includes the use of oligonucleotides of the present invention in antisense and homologous recombination constructs and methods.

专利号:WO-2021038306-A1
优先权日:2019-08-28
标 题 :Selenophenochromene phosphonic acids, preparation and use as antiproliferative agents
发明人:ARSENJANS PAVELS; DOMRACEVA ILONA; PAEGLE EDGARS
权利人:LATVIAN INST ORGANIC SYNTHESIS
摘要:The present invention relates to a novel selenophenochromene phosphonic acids as antiproliferative agents, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment or prevention of various diseases and disorders by administration of such substances.
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参考文献:10.1007/s00284-005-0078-y
摘要:Barreto HM, Siqueira-Junior JP. Protective effect of furocoumarins against 254-nm ultraviolet in Staphylococcus aureus. Curr Microbiol. 2006 Jan;52(1):40–4. doi: 10.1007/s00284-005-0078-y.
参考文献:10.1055/s-2005-871295
摘要:Chou HC, Chen JJ, Duh CY, Huang TF, Chen IS. Cytotoxic and anti-platelet aggregation constituents from the root wood of Melicope semecarpifolia. Planta Med. 2005 Nov;71(11):1078–81. doi: 10.1055/s-2005-871295.
参考文献:10.4103/0019-5154.82498
摘要:Zhang R, Zhu W. Phytophotodermatitis due to chinese herbal medicine decoction. Indian J Dermatol. 2011 May;56(3):329–31.
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