CAS: 49633-25-2; 3-Isopropylpyrazole

相似化合物

91724-94-6 15802-80-9 17536-00-4

上下游产品

CAS号5782-56-9 1-(Dimethylamin... | CAS号2644-70-4 盐酸肼 | CAS号38664-64-1 (E)-1-(dimethyl... | CAS号563-80-4 甲基异丙基甲酮 | CAS号1186-70-5 二(二甲基氨基)甲氧基甲烷 | CAS号109-94-4 甲酸乙酯 | CAS号107073-66-5 α,γ-dipyrrolidi... | CAS号75-26-3 2-溴丙烷 | CAS号308847-51-0 1-[bis(3-propan... | CAS号922520-04-5 4-羟基-7-甲氧基-8-甲基...

1-Dimethylamino-4-Methyl-1-Penten-3-On置于盐酸肼,硫酸体系中,用 水 作为反应溶剂,化学反应 2.0H,以94%的收率获得产物3-异丙基吡唑
参考文献: Macrocyclic Serine Protease Inhibitors[fr] Inhibiteurs Macrocycliques De La Sérine Protéase
标题: Macrocyclic Serine Protease Inhibitors[fr] Inhibiteurs Macrocycliques De La Sérine Protéase
摘要:本文提供了大环丝氨酸蛋白酶抑制剂化合物,例如,Formula I的药物组合物,以及其制备方法.还提供了它们用于治疗宿主hcv感染的方法.

专利信息

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:US-12054833-B2
优先权日:2020-07-29
标 题:Catalyst for synthesizing organic carbonate and method of producing thereof, electrode for synthesizing organic carbonate, cell for synthesizing organic carbonate, method of producing organic carbonate, and synthesis system
发明人：FUJINUMA NAOHIRO
权利人:SEKISUI CHEMICAL CO LTD
摘要:An organic carbonate synthesis catalyst for electrochemically synthesizing an organic carbonate from carbon monoxide, comprises: an active particle containing a metal element; and a porous carbon supporting the active particle.

专利号:US-9951088-B2
优先权日:2012-05-09
标题 :D2 receptor modulators and methods of use thereof in the treatment of diseases and disorders
发明人：JONES PHILIP G; LEW ROBERT; SPEAR KERRY L; XIE LINGHONG
权利人:SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and neurological disorders, including, but not limited to, e.g., psychosis, schizophrenia, depression, movement disorders, and Parkinson's disease.

专利号:US-12215435-B2
优先权日:2021-09-09
标 题 :Electrochemical cell, method for producing carbonyl compound, and synthesis system
发明人：FUJINUMA NAOHIRO
权利人:SEKISUI CHEMICAL CO LTD
摘要:The electrochemical cell is an electrochemical cell which electrochemically synthesizes at least one carbonyl compound selected from the group consisting of organic carbonates and organic oxalates from carbon monoxide, and has an electrolyte solution containing a redox species and a catalyst, and an electrode.

专利号:US-8383643-B2
优先权日:2009-07-28
标题 :Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase
发明人：LECLERC JEAN-PHILIPPE; LI CHUN-SING; MORADEI OSCAR MIGUEL
权利人:MERCK CANADA INC; LECLERC JEAN-PHILIPPE; LI CHUN-SING; MORADEI OSCAR MIGUEL
摘要:Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.