CAS: 494-47-3; (E)-1-(Furan-2-yl)-N-[furan-2-Yl-[(E)-Furan-2-Ylmethylideneamino]Methyl]Methanimine

该化合物是一种有机化合物,其独特结构包括两个呋喃环和甲烷基骨,其中含有氧气的五人芳香环的存在有助于其潜在的反应和生物活动.这种化合物一般在室温下是固体的,可能根据纯度和具体配制表现出多种颜色.已知该化合物在有机合成中的潜在应用以及作为制药和农用化学品开发的一个构件.该化合物还可能显示出有趣的特性,如荧光或光化学活动,因为由呋喃环形成的同系.此外,其矿群可以参与各种化学反应,包括核仁替代和凝聚反应,使其在合成化学中成为多用途的中间体.在处理和储存时,应参考安全数据,作为化学物质的处理和储存.

英文名称(E)-1-(Furan-2-yl)-N-[furan-2-Yl-[(E)-Furan-2-Ylmethylideneamino]Methyl]Methanimine
中文名称三呋喃甲醛二亚胺
IUPAC名称Methanediamine, 1-(2-furanyl)-N,N'-bis(2-furanylmethylene)- (9CI)
其它别名1-(2-furanyl)-n,n’-bis(2-furanylmethylene)-methanediamin; 2-(bis(furfurylidenamino))methylfuran; furfuramide; n,n’-difurfurylidene-2-furanmethanediamin; HYDROFURAMIDE; 1,3,5-tri(2-furyl)-2,4-diazapenta-1,4-diene; N,N'-Difurfurylidene(2-furyl)methanediamine
CAS编号494-47-3
MFCD编号:MFCD00020938
EINECS号:207-790-8
分子式:C15H12N2O3分子量:268.27
产品CID: 1481260
产品分类有机原料 → 有机杂环化合物 → 杂芳族化合物

相似结构搜索
InChIKey: CYGDSXFTXXFMNI-UHFFFAOYSA-N
InChI=1S/C15H12N2O3/c1-4-12(18-7-1)10-16-15(14-6-3-9-20-14)17-11-13-5-2-8-19-13/h1-11,15H/b16-10+,17-11+
计算化学: 氢键受体数5.0氢键供体数*可旋转键数5.0

物理性质

熔点117°
沸点336.603 °C at 760 mmHg
闪点157.372 °C
密度1.234 g/cm3
PSA:64.14
LogP:3.7024
折射率1.599
蒸汽压0mmHg at 25°C
外观形态淡-棕色至白色粉末
储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
产品应用该化合物是一种生化物.

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号4795-29-3 2-四氢糠胺 | CAS号5343-16-8 2-Furanmethanam... | CAS号18240-50-1 N,N-双(2-呋喃基甲基)胺 | CAS号617-89-0 糠胺 | CAS号550-23-2 2,4,5-tris(2-fu...

合成工艺路线路线简述

合成目标产物 Hydrofuramide 主要起始原料 Furfural
(文献来源)合成步骤主要原料 Furfural

📜糠醛置于ammonium Hydroxide体系中,化学反应 5.0H,反应生成三呋喃甲醛二亚胺
参考文献:Studies On The Reaction Of Diimines With Thiourea: Synthesis And Solvent-Induced Cis/trans-Isomerization Of 1,3,5-Triazinane-2-Thiones
标题:Studies On The Reaction Of Diimines With Thiourea: Synthesis And Solvent-Induced Cis/trans-Isomerization Of 1,3,5-Triazinane-2-Thiones
摘要:研究了n,N'-双(芳基甲烯基)芳基亚胺与硫脲在甲醇中回流反应.该反应得到了4,6-二取代1,3,5-三嗪烷-2-硫酮的二消旋体混合物,收率非常好.通过NMR分析,在cdcl3溶液中检测到了4,6-二苯基-1,3,5-三嗪烷-2-硫酮的两个二消旋异构体.根据NMR研究,顺式二消旋异构体经历了一个溶剂诱导的顺/反异构化过程,在dmso中反应生成反式二消旋异构体.反式二消旋异构体的立体化学通过x射线晶体学分析确定.
DOI:10.1055/s-0029-1216884

专利信息

专利号:US-6008347-A
优先权日:1993-04-23
标题:N-substituted 2-azetidinones
发明人：REY ALLAN W; VEMISHETTI PURUSHOTHAM; DROGHINI ROBERTO
权利人:BRISTOL MYERS SQUIBB CO
摘要:The present invention provides novel cis-N-iminomethyl-3,4-disubstituted-2-azetidinones, and their use in the preparation of N-acyl-2-azetidinones, intermediates in the semi-synthesis of taxol and taxol derivatives.

专利号:GB-412914-A
优先权日:1932-06-28
标题 :Process for the catalytic synthesis of furfuryl-amines

专利号:US-5412092-A
优先权日:1993-04-23
标题:N-substituted 2-azetidinones
发明人：REY ALLAN W; VEMISHETTI PURUSHOTHAM; DROGHINI ROBERTO
权利人:BRISTOL MYERS SQUIBB CO
摘要:Novel cis compound having the formula: ##STR1## wherein R 1 is alkyl, haloalkyl, cycloalkyl, aryl or a carbohydrate derivative; X is O, N, S, C(O)O or a direct bond; and R 2 is aryl, substituted aryl or heteroaryl are useful in the synthesis of taxol and taxol derivatives.

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供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Self-Regulated Catalysis For The Selective Synthesis Of Primary Amines From Carbonyl Compounds
作者:Mingxia Gao,Xiuquan Jia,Jiping Ma,Xiaomeng Fan,Jin Gao,Jie Xu
摘要:Most Current Processes For The General Synthesis Of Primary Amines By Reductive Amination Are Performed With Enormously Excessive Amounts Of Hazardous Ammonia. It Remains Unclear How Catalysts Should Be Designed To Regulate Amination Reaction Dynamics At A Low Ammonia-To-Substrate Ratio For The Quantitative Synthesis Of Primary Amines From The Corresponding Carbonyl Compounds. Herein We Show A Facile

合成参考文献

参考文献:10.1007/bf00509732
摘要:Varlamov GD, Mamatov YM, Shashkov AS. Structure of “furfuramide” and “furfurine”. Chemistry of Heterocyclic Compounds. 1978 Nov;14(11):1184–7. doi: 10.1007/bf00509732.