CAS: 42079-78-7; 5-Methoxy-2-Phenyl-4H-Chromen-4-One

该化合物是一种属于氟氯素类的化学化合物,其特征是其结构包括一个带甲氧基组的氟拉夫骨,在5号位置有甲氧基组;该化合物以其潜在的生物活动而著称,包括抗氧化剂,抗氟化物和抗癌特性,这些特性引起了药理研究的兴趣;该化合物通常是黄色晶体固体,在有机溶剂中表现出中等溶解性,同时在水中不易溶解;甲基氧组的存在可影响其再活动以及与生物系统的相互作用;5-甲基氧氟拉夫酮经常因其对各种细胞路径及其潜在治疗用途的影响而受到研究;与许多氟氧氟化物一样,该化合物还可能有助于与植物食物饮食摄入相关的健康惠益;安全和毒性简介是其应用中的基本考虑因素;目前正在进行进一步的研究,以充分阐明其在医药和健康方面的行动和潜在用途机制.

英文名称5-Methoxy-2-Phenyl-4H-Chromen-4-One
中文名称5-甲氧基黄酮
IUPAC名称5-methoxy-2-phenyl-4H-chromen-4-one
其它别名Flavone,5-methoxy- (7CI); 5-Methoxyflavone
CAS编号42079-78-7
MFCD编号:MFCD00016942
EINECS号:255-652-0
分子式:C16H12O3分子量:252.27
产品CID: 1434290
产品分类生物化工 → 提取物

相似结构搜索
产品信息参考;;;
InChIKey: XRQSPUXANRGDAV-UHFFFAOYSA-N
InChI=1S/C16H12O3/c1-18-13-8-5-9-14-16(13)12(17)10-15(19-14)11-6-3-2-4-7-11/h2-10H,1H3
计算化学: 氢键受体数3.0氢键供体数*可旋转键数2.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319-H335
防范说明P261-P280a-P304+P340-P305+P351+P338-P405-P501a
危险品标志Xi
安全声明26-36/37/39-36
危险类别码36/37/38
WGK Germany3

上下游产品

2'-Hydroxy-6'-methoxychalcone 1-(2-benzoyloxy-6-methoxy-phenyl)-ethanone phenylpropiolyl chloride 1,3-Dimethoxybenzene 5-Hydroxyflavone benzopyran-7-one1a,7a-Dihydro-6-methoxy-1a-phenyl-7H-oxireno1benzopyran-7-one 5-methoxy-2-phenyl-4-quinolone primetin 5-amino-2-bromopyrazine 2-bromo-5-(3,4,5-tridodecyloxyphenylethynyl)pyrazine 2-(5-bromo-2-pyrazinylethynyl)-5-(3,4,5-tridodecyloxyphenylethynyl)pyrazine 2-iodo-5-methoxy-pyrazine 5'-iodo-3-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl

合成工艺路线路线简述

📜1-(2-Benzoyloxy-6-Methoxy-Phenyl)-Ethanone置于氢氧化钾,硫酸,溶剂黄146体系中,用吡啶作为反应溶剂,化学反应生成 5-甲氧基黄酮
参考文献:Epoxidation Of Flavones By Dimethyldioxirane
标题:Epoxidation Of Flavones By Dimethyldioxirane
摘要:The Synthesis Of Epoxides 2 By Epoxidation Of Flavones 1 With Isolated Dimethyldioxirane (As Acetone Solution) At Subambient Temperatures Is Reported. These Labile Epoxides Were Isolated And Completely Characterized By Uv,Ir,H-1 And C-13 NMR,Ms,And C,H Analyses. Warming To Room Temperature Led To Rearrangement To Afford Quantitatively The 3-Hydroxyflavones 3B,H,I,N. Treatment Of The Epoxides 2B,F With Methanol Led To The 3-Hydroxy-2-Methoxyflavanones 4B,F As A Mixture Of Cis And Trans Isomers.
DOI:10.1021/jo00026A020