CAS: 39860-99-6; 10-(3-(4-(2-Hydroxyethyl)Piperidin-1-yl)Propyl)-N,N-Dimethyl-10H-Phenothiazine-2-Sulfonamide

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    专利号:US-2023271983-A1
    优先权日:2020-07-29
    标题 :Functionalized isonitriles and products, preparation and uses thereof
    发明人:SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
    权利人:UNIV SANTIAGO COMPOSTELA
    摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

    专利号:WO-2025118034-A1
    优先权日:2023-12-06
    标题 :Compounds active at the serotonergic 5-ht2a receptor
    发明人:JORGENSON WILLIAM; TAN JINLONG; WHISH LACHLAN; BANISTER SAMUEL
    权利人:Psylo Pty Ltd
    摘要:The present disclosure relates to compounds of formula (I), their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.

    专利号:WO-2023230649-A1
    优先权日:2022-05-30
    标题:Compounds
    发明人:BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
    权利人:Psylo Pty Ltd
    摘要:The present disclosure relates to compounds of formula (I), their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.

    专利号:US-12415804-B2
    优先权日:2023-06-28
    标题 :Compounds for activating a serotonin receptor
    发明人:BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
    权利人:Psylo Pty Ltd
    摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.

    专利号:US-12428380-B2
    优先权日:2023-06-28
    标 题 :Compounds
    发明人:BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
    权利人:Psylo Pty Ltd
    摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.

    专利号:US-2025101038-A1
    优先权日:2021-12-24
    标 题 :Compounds
    发明人:BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG
    权利人:Psylo Pty Ltd
    摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.

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    主要参考文献


    1: Dinesh M, David A, Quraishi SN. Depot pipotiazine palmitate and undecylenate for schizophrenia. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD001720. Review.

    合成参考文献


    参考文献:10.2165/00003495-199447050-00004
    摘要:Davis JM, Matalon L, Watanabe MD, Blake L, Metalon L [corrected to Matalon L]. Depot antipsychotic drugs. Place in therapy. Drugs. 1994 May;47(5):741–73. doi: 10.2165/00003495-199447050-00004.
    参考文献:10.1007/bf02245006
    摘要:Leysen JE, Janssen PM, Schotte A, Luyten WH, Megens AA. Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors. Psychopharmacology (Berl). 1993;112(1 Suppl):S40–54. doi: 10.1007/bf02245006.
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