CAS: 3733-81-1; Defosfamide

专利信息

专利号:US-2022400732-A1
优先权日:2019-03-21
标题:Anti-fructose therapy for colorectal and small intestine cancers
发明人：GONCALVES MARCUS; CANTLEY LEWIS C; YUN JIHYE
权利人:UNIV CORNELL
摘要:As described herein ingestion of high amounts of sugar, especially fructose, can increase the growth of intestinal tumors. Such cancer growth can be inhibited or prevented by limiting the amounts of sugar and amino acids ingested, by inhibiting ketohexokinase (KHK), fructose transport (via GLUT5), fatty acid synthesis (via FASN), phosphoinositide 3-kinases (PI3K), or by limiting amounts of sugar and amino acids ingested while also receiving KHK inhibitors, GLUT5 inhibitors, FASN inhibitors, PI3K inhibitors, or a combination of such inhibitors.

专利号:CN-105530942-A
优先权日:2013-08-26
标 题:Pharmaceutical compositions comprising macrolide diastereomers, methods of their synthesis and therapeutic uses