CAS: 3038-47-9; 2-(Trifluoromethyl)Phenylacetonitrile

上下游产品

CAS号773837-37-9 sodium cyanide | CAS号395-44-8 2-(三氟甲基)苄溴 | CAS号346-06-5 邻三氟甲基苯甲醇 | CAS号151-50-8 氰化钾 | CAS号21742-00-7 2-(三氟甲基)氯苄 | CAS号395-47-1 (2-(trifluorome... | CAS号3038-48-0 2-三氟甲基苯乙酸 | CAS号124276-63-7 1-[2-(三氟甲基)苯基]环丙烷甲腈 | CAS号774-18-5 2-(三氟甲基)苯乙胺

(2-(Trifluoromethyl)Phenyl)Magnesium Bromide 以 二甲基亚砜 用作溶剂,化学反应生成2-(三氟甲基)苯基乙腈
参考文献:Van Der Stelt,C. Et Al.,Arzneimittel-Forschung/drug Research,1965,Vol. 15,P. 1251-1253
标题:Van Der Stelt,C. Et Al.,Arzneimittel-Forschung/drug Research,1965,Vol. 15,P. 1251-1253

专利信息

专利号:US-2011172427-A1
优先权日:2008-08-27
标 题 :Process for preparing certain cinnamide compounds
发明人：NAKAMURA TAIJU; MATSUDA MASAAKI; HU YONGBO; HASEGAWA DAIJU; HOSHINO YORIHISA; INANAGA KAZATO; ISOMURA MINETAKA; SATO NOBUAKI; YOSHIZAWA KAZUHIRO; MONIZ GEORGE A; WILKIE GORDON D; FANG FRANCIS G; NISHIKAWA YOSHIHIRO
权利人:EISAI R&D MAN CO LTD
摘要:This invention relates to a new synthesis, intermediates and precursors leading to a mixture of the compounds 11 and 12 as shown below. It also relates to the resolution of the stereoisomeric mixture to provide in substantial stereochemical purity compound 12. The synthesis of the invention involves preparation of compound 7 and compound 10 as shown below and their reaction to prepare a mixture of compound 11 and compound 12.

专利号:WO-2021078995-A1
优先权日:2019-10-25
标 题 :Selective polypeptide synthesis stalling assay and compound
发明人：STROUS GERARDUS JACOBUS ANTONIUS MARIA; MOL JAN ADRIANUS; VAN DER VELDEN LIEKE MARIE; KLUMPERMAN JUDITH; MAAS PETRUS EMMANUEL MARIE; PIET DENNIS PATRICK; DE KLERK-SPRENKELS NANDA ELISABETH; TIJHUIS JOHANN HEINRICH; VIÉTOR HENDRIK ENGELBERTUS; MAURICE MADELON MARIA; VAN DER KRIFT FELIX
权利人:UMC UTRECHT HOLDING BV; UNIV UTRECHT HOLDING BV; BIMINI BIOTECH B V
摘要:The invention relates to compounds, in particular pyrimidine-2,4-diamines, analogues and salts thereof and pharmaceutical compositions comprising pyrimidine-2,4-diamines analogues and salts thereof for use in the treatment and prevention of a disease, in particular a growth hormone receptor-dependent condition. The invention also relates to methods of using these compounds and compositions to treat physiological disorders related to the amount or activity of growth hormone. In a particular embodiment, the invention relates to a compound according to formula 1 for use in the treatment or prevention of a disease in a subject.

专利号:US-7777060-B2
优先权日:2007-02-14
标题:Platinum analogs with bis-nitrile-containing ligands
发明人：CHEN XINGHAI; PETLURU PAVANKUMAR N V; HUANG QIULI; NARKUNAN KESAVARAM; HAUSHEER FREDERICK
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based analogs possessing two nitrile substituent groups (bis-nitrile) covalently-bonded to the platinum. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as quantitative in vitro IC50 data.