CAS: 27996-87-8; 2-Fluoro-5-Nitrobenzaldehyde

上下游产品

CAS号6361-21-3 2-氯-5-硝基苯甲醛 | CAS号446-52-6 邻氟苯甲醛 | CAS号455-88-9 2-氟-5-硝基甲苯 | CAS号30742-59-7 5-硝基-2-(吡咯烷-1-基)苯甲醛 | CAS号84832-00-8 5-氨基-2-氟苄醇 | CAS号5401-94-5 5-硝基吲唑 | CAS号63878-73-9 2-氟-5-硝基苄醇 | CAS号25785-09-5 5-硝基苯并[b]噻吩-2-羧酸乙酯 | CAS号23856-20-4 1-苄基-5-硝基-1h-吲唑 | CAS号759456-60-5 (5-AMINO-2-MORP... | CAS号802541-81-7 (5-AMINO-2-(4-M... | CAS号84459-36-9 7-nitro-10-phen... | CAS号900174-36-9 5-nitro-2-propa...

2-氯-5-硝基苯甲醛置于potassium Fluoride体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应生成2-氟-5-硝基苯甲醛
参考文献:喹唑啉或喹啉发色团作为π偶联桥用于染料敏化太阳能电池的有机染料的比较研究
标题:喹唑啉或喹啉发色团作为π偶联桥用于染料敏化太阳能电池的有机染料的比较研究
摘要:设计并合成了一系列新的有机d-π-a染料,它们在生色团中以喹唑啉或喹啉为共轭桥,以二苯胺部分作为电子供体,并以氰基乙酸单元作为电子受体,用于染料中的光转化.敏化太阳能电池(dssc).系统地研究了这些染料的吸收光谱,密度泛函理论计算,电化学和光伏性质.在这四种染料中,基于带有丁氧基的喹啉染料的敏化太阳能电池的短路光电流密度为7.04 Ma Cm-2,开路电压为0.52 V,填充系数为0.69,对应于总转换效率用我的2.51%-/一世3-在标准的整体am 1.5辐照下(100 Mw Cm-2),基于氧化还原对的液态电解质,不含4-叔丁基吡啶添加剂.以4,4'-二丁氧基二苯胺为供体,以喹啉单元为π桥的染料的光电性能高于其他光敏剂,这主要归因于较高的摩尔消光系数和较宽的吸收带.实验结果表明,合理的分子工程对于构建高效的电荷转移敏化剂至关重要.
Doi:10.1016/j.Dyepig.2015.09.002

专利信息

专利号:US-4699984-A
优先权日:1984-09-17
标 题 :Preparation of intermediates to 6-fluoro-7-(2,6-dimethylpyridyl)quinoline carboxylic acids and compounds
发明人：SINGH BALDEV
权利人:STERLING DRUG INC
摘要:Shown is the process which comprises heating 4-(2-fluorophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylic acid to produce a mixture of 4-(2-fluorophenyl)-2,6-dimethylpyridine and 2,4-dimethyl-5H-[1]benzopyrano[3,4-c]pyridin-5-one, separating the components of said mixture and nitrating 4-(2-fluorophenyl)-2,6-dimethylpyridine to produce 4-(2-fluoro-5-nitrophenyl)-2,6-dimethylpyridine. Also shown are the 3-step synthesis of 4-(2-fluorophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylic acid from 2-fluorobenzaldehyde and the five step synthesis of 1-ethyl-6-fluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid, a highly potent antibacterial agent, starting with 4-(2-fluoro-5-nitrophenyl)-2,6-dimethylpyridine. Other intermediates shown in said five step synthesis include 3-(2,6-dimethyl-4-pyridinyl)-4-fluorobenzeneamine and diethyl 4-fluoro-3-(2,6-dimethyl-4-pyridinyl)anilinomethylenemalonate.

专利号:US-2025170267-A1
优先权日:2022-02-28
标 题 :Antibody-drug conjugate precursor and intermediate for synthesis thereof
发明人：TSUZAKI YASUNORI; MIZUNO GEN; KASHIWAGI TAKAMASA; TANAKA MASAYUKI; SHIMIZU HAYATO; NONOUCHI SHIMPEI; MATSUSHITA TAKASHI; KIMURA TOMIO
权利人:UBE CORP
摘要:A method for improving the stability of an antibody-drug conjugate in a living body, and a conjugate precursor for producing a stabilized antibody-drug conjugate. An antibody-drug conjugate precursor represented by the following general formula (I) or a salt thereof, a synthetic intermediate thereof or a salt thereof, n Z-L-D  (I)n n where Z is a reactive group which can react with a functional group present in an antibody or a modified antibody; D is an antitumor drug residue in which one hydrogen atom or one hydroxy group is removed from any position of an antitumor drug molecule or an analog thereof or a derivative thereof; L is a linker which links Z to D; and at least any one of D and L has one or more lactonyl group(s) at any position(s) as substituent(s) or protecting group(s).

专利号:RU-2105007-C1
优先权日:1991-10-10
标题:Method of synthesis of benzo-[b]-naphthyridine derivatives and derivatives of benzo-[b]-naphthyridines

专利号:US-5442070-A
优先权日:1991-10-10
标 题:Derivatives of fluoro-quinoline carboxylic-3-acid and preparation therefor
发明人：DAUBIE CHRISTOPHE; LEGRAND JEAN-JACQUES; PEMBERTON CLIVE
权利人:BELLON LABOR SA ROGER
摘要:This invention relates to new derivatives of fluoro quinoline carboxylic-3 acid having general formula (I), ##STR1## wherein R is a hydrogen atom or an alkyl radical and Hal is a halogen atom, as well as salts thereof, when they exist, preparation thereof and utilization as synthesis intermediary.

专利号:US-10227344-B2
优先权日:2016-06-24
标题 :CK2 inhibitors, compositions and methods thereof
发明人：WEBBER STEPHEN E; TAO XUELIANG; BRIN ELENA
权利人:POLARIS PHARMACEUTICALS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula (I), or a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof. n nFor Formula (I) compounds R 1 , R 2 , R 3 , Ar and Z are as defined in the specification. The inventive Formula (I) compounds are inhibitors of CK2 and find utility in any number of therapeutic applications, including but not limited to treatment of proliferative disorders such as cancer, inflammation and immunological disorders.

专利号:CN-116396171-B
优先权日:2023-03-29
标题:A kind of synthesis method of 2-fluoro-5-nitrobenzaldehyde