专利号:US-9981935-B2 优先权日:2013-07-05 标 题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids 发明人:MEDLOCK JONATHAN ALAN; LETINOIS ULLA; NETSCHER THOMAS; BONRATH WERNER 权利人:DSM IP ASSETS BV 摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.
专利号:US-2004049049-A1 优先权日:2002-06-14 标 题 :Stereoselective synthesis of 1,2-disubstituted cycloalkyls 发明人:JURAYJ JURJUS F; FARHAN EMILE; SHARMA PRADEEP K 权利人:JOHNSON MATTHEY PHARMACEUTICAL 摘要:A stereoselectively method of preparing a 1,2-disubstituted cycloalkyl, such as aminocycloalkyl ether compounds, from a trans-1,2-disubstituted cycloalkyl or a cis-2-substituted cycloalkanol. For example, a stereoselective method of preparing 1R-(3R-hydroxypyrrolidin-1-yl)-2R-(2-phenylethoxy)-cyclohexane from 1R,2R-cyclohexanediol or from meso-cis-1,2-cyclohexanediol is described. Aminocycloalkyl ethers, such as 1R-(3R-hydroxypyrrolidin-1-yl)-2R-(2-phenylethoxy)-cyclohexane, can be used to treat cardiac disease.
专利号:US-12252583-B2 优先权日:2018-06-20 标题:Method of making mixture of polymers 发明人:FONTANA GIOVANNI; GALIMBERTI MARCO; TORTELLI VITO 权利人:SOLVAY SPECIALTY POLYMERS IT 摘要:The present invention relates to a process for the synthesis of partially and fully fluorinated polyether (PFPE) polymers comprising cyclic moieties in the backbone chain, to PFPE polymers obtained therefrom and to the use of said PFPE polymers as intermediate compounds for the manufacture of additives for plastic and glass coating.
专利号:US-7456298-B2 优先权日:2002-06-03 标题:Synthesis of acetonides from aryl silanes 发明人:MCAULIFFE JOSEPH C; WHITED GREGORY M; SMITH WYATT CHARLES 权利人:GENENCOR INT 摘要:The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for converting silane cis-diols to the corresponding catechols and the compounds produced thereby. The present invention also provides chemical methods for the conversion of said silane cis-diols and acetonide compounds to epoxy, saturated and otherwise modified derivatives. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims.
专利号:US-9051656-B2 优先权日:2009-07-23 标题 :Electrochemical synthesis of aryl-alkyl surfacant precursor 发明人:BHAVARAJU SAI; KARANJIKAR MUKUND; CHITTA PALLAVI 权利人:BHAVARAJU SAI; KARANJIKAR MUKUND; CHITTA PALLAVI; CERAMATEC INC 摘要:An aryl-alkyl (R—Ar) hydrocarbon is prepared by an electrosynthesis process in an electrolytic cell having an alkali ion conductive membrane positioned between an anolyte compartment configured with an anode and a catholyte compartment configured with a cathode. An anolyte solution containing an alkali metal salt of an alkyl carboxylic acid and an aryl compound is introduced into the anolyte compartment. The aryl compound may include an alkali metal salt of an aryl carboxylic acid, an arene (aromatic) hydrocarbon, or an aryl alkali metal adduct (Ar − M + ). The anolyte solution undergoes electrolytic decarboxylation to form an alkyl radical. The alkyl radical reacts with the aryl compound to produce the aryl-alkyl hydrocarbon.
专利号:US-2004033574-A1 优先权日:2002-06-03 标题 :Synthesis of cis-diols from aryl silanes
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合成参考文献
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