CAS: 134-47-4; 7,7'-(Carbonylbis(Azanediyl))Bis(4-Hydroxynaphthalene-2-Sulfonic Acid)

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CAS号32315-10-9 三光气 | CAS号87-02-5 7-氨基-4-羟基-2-萘磺酸 | CAS号75-44-5 光气

三光气,7-氨基-4-羟基-2-萘磺酸置于sodium Hydroxide体系中,化学反应 6.0H,以90%的收率获得猩红酸
参考文献:Small Molecule Inhibitors Of Histone Arginine Methyltransferases: Homology Modeling,Molecular Docking,Binding Mode Analysis,And Biological Evaluations
标题:Small Molecule Inhibitors Of Histone Arginine Methyltransferases: Homology Modeling,Molecular Docking,Binding Mode Analysis,And Biological Evaluations
摘要:The Screening Of The Inhibition Capabilities Of Dye-Like Small Molecules From A Focused Library Against Both Human Prmt1 And Aspergillus Nidulans Rmta Is Reported As Well As Molecular Modeling Studies (Homology Modeling,Molecular Docking,And 3-D Qsar) Of The Catalytic Domain Of The Prmt1 Fungal Homologue Rmta. The Good Correlation Between Computational And Biological Results Makes Rmta A Reliable Tool For Screening Arginine Methyltransferase Inhibitors. In Addition,The Binding Mode Analyses Of Tested Derivatives Reveal The Crucial Role Of Two Regions,The Pocket Formed By Ile12,His13,Met16,And Thr49 And The Sam Cisteinic Binding Site Subsite. These Regions Should Be Taken Into Account In The Design Of Novel Prmt Inhibitors.
Doi:10.1021/jm061213N

专利信息

专利号:US-2024174698-A1
优先权日:2022-09-23
标题 :Modular synthesis of 1,2-azaborines via ring-opening bn-isostere benzannulation
发明人：DONG GUANGBIN; LYU HAIRONG; CHEN ZHIJIE; WU YIFEI; CHOI SHINYOUNG
权利人:UNIV CHICAGO
摘要:The present disclosure relates generally to 1,2-azaborines and methods of making the same.

专利号:US-2023159678-A1
优先权日:2020-06-19
标题:Methods of polymerization with aromatic thiol initiators
发明人：BOWMAN CHRISTOPHER N; LOVE DILLON
权利人:UNIV COLORADO REGENTS
摘要:Provided herein are methods of using aryl thiols as photoinitiators. The thiol compounds are useful as oxygen insen-sitive photoinitiators for applications such as bulk polymerizations and for specialty polymer synthesis by preparing aromatic thiol functionalized macroinitiators.

专利号:US-2023132381-A9
优先权日:2016-07-08
标 题 :Synthesis of functionalizable or functionalized poly(3,4-ethylenedioxythiphene)-based polymers and monomers therefor

专利号:US-2024342119-A1
优先权日:2021-08-02
标 题:Composition for treating hypertrophic scars and keloids comprising benzhydryl thioacetamide compound as active ingredient
发明人：KIM SEONG-JIN; KIM SEON-MYUNG
权利人:CELLIONBIOMED INC
摘要:The present invention relates to a composition for treating hypertrophic scars and keloids, comprising a benzhydryl thioacetamide compound as an active ingredient. The benzhydryl thioacetamide compound inhibits cell proliferation and an increase in intracellular Ca 2+ concentration, in fibroblasts, keratinocytes and vascular endothelial cells that are involved in skin fibrosis, and inhibits the synthesis of collagen, which is the extracellular matrix, and thus has the effect of effectively treating intractable hypertrophic scars and keloids.

专利号:CN-112839932-B
优先权日:2018-08-17
标题:Synthesis of Chromanol Derivatives

专利号:CN-112888679-B
优先权日:2018-08-17
标题:Synthesis of chromanol derivatives