CAS: 86060-85-7; Fmoc-Gly-Opfp

相似化合物

159631-29-5 125043-04-1 86060-86-8

上下游产品

CAS号771-61-9 五氟苯酚 | CAS号29022-11-5 Fm°C-甘氨酸 | CAS号103321-49-9 N-(芴甲氧羰基)甘氨酰氯 | CAS号244633-31-6 4-硝基苯磺酸五氟苯酯 | CAS号88744-04-1 9-芴基甲基五氟苯基碳酸酯 | CAS号75539-79-6 Z-D-PHE-PHE-GLY-OH

📜Fmoc-甘氨酸置于吡啶,氯化亚砜体系中,用 四氢呋喃,二氯甲烷 作为反应溶剂,化学反应生成 N-芴甲氧羰基甘氨酸五氟苯酯
参考文献:一种新的简便的一锅制备fmoc氨基酸的五氟苯基(pfp)和3,4-二氢-4-氧代1,2,3-苯并三嗪-3-基(dhbt)酯.
标题:一种新的简便的一锅制备fmoc氨基酸的五氟苯基(pfp)和3,4-二氢-4-氧代1,2,3-苯并三嗪-3-基(dhbt)酯.
摘要:对于n五氟苯基和3,4-二氢-4-氧代-1,2,3-苯并三嗪-3-基酯的制备的新的一锅程序α-9-芴氨基酸不带有侧链保护基团是描述.该方法无需使用高度致敏的dcc,即可以高收率和纯度获得所需的活化酯.
DOI:10.1016/0040-4039(91)80788-8

专利信息

专利号:US-6515039-B1
优先权日:1998-08-28
标 题:Method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material
发明人：ULBRICHT MATHIAS; VOLKMER-ENGERT RUDOLF; GERMEROTH LOTHAR; WENSCHUH HOLGER
权利人:POLY AN GMBH
摘要:The invention relates to a method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material. According to the method, a continuous polymeric solid phase supporting material is prepared, the material comprising a matrix of a supporting polymeric material and graft copolymer chains covalently bound to the supporting matrix, the graft copolymer chains having reactive groups being able to react with organic compounds, thereby forming spatially defined reaction sites. The method then comprises the sequential spotting of synthesis building blocks or reagents at the various reaction sites on the continuous solid phase supporting material to yield a substrate library of compounds bound to the solid phase supporting material, whereby each reaction site on the continuous solid phase supporting material determines the composition of the synthesized compound, which is bound directly on the supporting matrix via the reactive groups of the graft polymer chain.

专利号:US-2003138880-A1
优先权日:2001-08-24
标 题:Solid-phase synthesis of oligosaccharides and glycopeptides using glycosynthases
发明人：WITHERS STEPHEN G; JENSEN KNUD J; PETERSEN LARS; TOLBORG JAKOB L
权利人:UNIV BRITISH COLUMBIA
摘要:The present invention provides materials and methods for the solid-phase synthesis of oligosaccharides and glycopeptides. Such materials and methods include mutant glycosidase enzymes, or “glycosynthases,â€? chemically-derivatized acceptor molecules, and specific solid support matrices.

专利号:US-5126273-A
优先权日:1986-02-03
标题 :Monitoring method for the synthesis of a linear conbination of amino acid residues
发明人：SHEPPARD ROBERT; MELDAHL MORTEN
权利人:NOVOBIOCHEM AG
摘要:A monitoring method for application in solid phase peptide synthesis. In one aspect, the synthesis starts with an amino acid residue protected by an N-alpha-amino protecting group and involves the steps: (a) removing the N-alpha-amino protecting group to obtain an N-alpha-amino group, (b) adding an amino acid residue protected by an N-alpha-amino protecting group, via a peptide bond, to the N-alpha-amino group obtained in step (a) by use of a reactive protected amio acid derivative, and (c) repeating steps (a) and (b). The reaction system includes 3-hydroxy-1,2,3-benzotriazin-4(3H)-one or a derivative thereof; and the color of the reaction system or of a component thereof is monitored during the synthesis.

专利号:WO-8704713-A2
优先权日:1986-02-03
标题 :Monitoring method for the synthesis of a linear combination of amino acid residues

专利号:EP-0708751-A1
优先权日:1993-07-16
标题:Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses

专利号:EP-0604552-A1
优先权日:1991-09-18
标 题 :PROCESS FOR THE SYNTHESIS OF VARIOUS COLLECTIONS OF OLIGOMERS.