CAS: 7658-08-4; (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxyhexanal

上下游产品

(2S,3S,4S,5S,6R)-2-methoxy-6-methyltetrahydro-2H-pyran-3,4,5-triol 1pseudo-ginsenoside-RS1 sulfuric acid D,L-rhamnose trifluoroacetylated 6-deoxymannose anti-O-benzyloxime trifluoroacetylated 6-deoxymannose syn-O-benzyloxime 5-Methylfurfural

📜白前苷b置于溶剂黄146体系中,用 水 作为反应溶剂,化学反应 2.0H,反应生成 6-脱氧-D-葡萄糖
参考文献:黄柏叶中具有保肝活性的类黄酮.
标题:黄柏叶中具有保肝活性的类黄酮.
摘要:一个新的黄酮醇苷命名visconoside C(1),具有七个已知黄酮醇苷一起,槲皮素-3-O-β-D吡喃葡萄糖苷7-O-α-升-Rhamnopyranoside(2),槲皮素-7-O-α-升-鼠李糖吡喃糖苷(3),黄芪甲素(4),山emp酚3-O-(4-O-乙酰基)-α-L-鼠李糖吡喃糖苷(5),山emp酚7-O-α-L-鼠李糖吡喃糖苷(6),山竹铁素(7)和山奈酚3-ö-β-D吡喃葡萄糖苷7-ö-α-升-Rhamnopyranoside(8)通过从所述叶片各种色谱方法分离黄花草其结构经ir,Uv,Hr-Esi-Ms和NMR(1D&2D)阐明l.实验.通过mtt法测定使用hepg2人肝癌细胞系1的细胞毒性和保肝活性.在25μm和50μm的浓度下,1对hepg2细胞具有细胞毒性活性(与阿霉素对照相比,细胞活力分别降低至22.2和23.0%),而在100μ
DOI:10.1080/14786419.2017.1283497

专利信息

专利号:US-2022395800-A1
优先权日:2019-11-04
标题:Device for automated synthesis of oligo- and polysaccharides
发明人：SEEBERGER PETER H; DANGLAD FLORES JOSE; LE MAI HOANG KIM; PARDO VARGAS ALONSO; SLETTEN ERIC; SALWICZEK MARIO
权利人:MAX PLANCK GESELLSCHAT ZU RFERDERUNG DER WSS E V; GlycoUniverse GmbH & Co KG&A
摘要:The present invention generally relates to automated synthesis technology, and more particularly, to a device and method for automated synthesis of oligo- and polysaccharides on a solid support. In particular the present invention relates to a device for automated synthesis of oligo- and polysaccharides on a solid support comprising a reaction vessel, a reagent storing component, a reagent delivery system, a cooling device for cooling reaction vessel, and a pre-cooling device for pre-cooling the reagents to be supplied.

专利号:EP-1421100-B1
优先权日:2001-08-21
标 题 :Chemical synthesis of solamargine
发明人：SHAHID MOHAMMED
权利人:GLYCOMED SCIENCES LTD
摘要:The present invention relates to the chemical synthesis of solanum glycosides, in particular to the synthesis of solamargine as well as to novel beta-monosaccharide Intermediate compounds.

专利号:US-6150130-A
优先权日:1993-12-27
标题 :DNA strands useful for the synthesis of xanthophylls and the process for producing the xanthophylls
发明人：MISAWA NORIHIKO; KONDO KEIJI; KAJIWARA SUSUMU; YOKOYAMA AKIHIRO
权利人:KIRIN BREWERY; MARINE BIOTECH INST CO LTD
摘要:Disclosed are the following DNA strands relating to the synthesis of keto group-containing xanthophylls such as astaxanthin and the like, and the techniques relating to the production of xanthophylls by genetic engineering: A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for converting a methylene group at the 4-position of a beta -ionone ring into a keto group. A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for converting a methylene group at the 4-position of a 3-hydroxy- beta -ionone ring into a keto group. A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for adding a hydroxyl group to the 3-carbon of a 4-keto- beta -ionone ring. It is possible to produce a variety of xanthophylls such as canthaxanthin, astaxanthin and the like by introducing the DNA strands into an appropriate microorganism such as Escherichia coli and the like.

专利号:WO-2018002957-A8
优先权日:2016-06-29
标 题 :A method for synthesis of 6-deoxy-l-hexoses from l-rhamnose
发明人：KULKARNI SUVARN SUBHASH; SANAPALA SOMESWARA RAO
权利人:INDIAN INST TECHNOLOGY BOMBAY
摘要:The present invention relates to a process for synthesis of 6-Deoxy-L-Hexoses from L-Rhamnose comprising the steps of optional regioselective protection of C2-, C3- and/or C4-OH of the L- Rhamnose of formula (1) to obtain compounds of formulae (2) and subjecting said compounds of formulae 2 to triflation followed by nitrite anion or water mediated inversion to obtain 6-deoxy- L-Hexoses of formulae (3).

专利号:US-10005807-B2
优先权日:2013-04-12
标题 :Synthesis of sialylated/fucosylated human milk oligosaccharides
发明人：CHASSAGNE PIERRE; KHANZHIN NIKOLAY; HEDEROS MARKUS JONDELIUS; CHAMPION ELISE; MATWIEJUK MARTIN; DEKANY GYULA
权利人:GLYCOM AS
摘要:An achemo-enzymatic synthesis of oligosaccharides of formula 1 is presented wherein R is selected from —OH, —N 3 and —OR 6 wherein R 6 is selected from allyl optionally substituted by one or more methyl, propargyl optionally substituted by one or more methyl, 2-trimethylsilyl-ethyl, —(CH 2) n —NH 2 and —(CH 2) n —N 3 wherein integer n is to 10, preferably 2 or 3, R is selected from sialyl moiety, —SO 3 H and —CH(R)—COOH wherein R is selected from H, alkyl and benzyl, R 2 is selected from H and fucosyl, R 3 is selected from H and sialyl, R 4 is selected from H and fucosyl, provided that at least one of R 3 and R 4 is H, and A is a divalent carbohydrate linker, having important biological activities and significant commercial value for the pharmaceutical and food industry.

专利号:WO-9516049-A1
优先权日:1993-12-08
标题 :Catalytic chemo-enzymatic asymmetric synthesis of carbohydrates
发明人：WONG CHI-HUEY; SHARPLESS BARRY K
权利人:SCRIPPS RESEARCH INST; WONG CHI HUEY; SHARPLESS BARRY K
摘要:A stereoselective synthesis of carbohydrates employs two key stereoselective steps, viz. an osmium-catalyzed asymmetric dihydroxylation (AD) of an alkene to form an aldol intermediate and an aldolase-catalyzed aldol addition reaction wherein the aldol intermediate is elongated by the addition of a ketone. Moreover, ketoses having four new stereocenters can be synthesized without the use of chiral starting materials. The stereoselectivity of the asymmetric dihydroxylation (AD) reaction is determined by the cis or trans (Z or E) stereoisomeric configuration of the alkene and by the choice of AD-mix, i.e., an AD-mix-α or AD-mix-β. The stereoselectivity of the aldolase-catalyzed addition reaction is determined by the choice of aldolase and by the stereochemistry of the aldol intermediate. Four aldolases with broad substrate specificity are sufficient to produce all possible enantiomeric combinations of the two hydroxymethylene stereocenters formed during the aldol addition reaction. Accordingly, a synthetic scheme combining an osmium-catalyzed asymmetric dihydroxylation (AD) reaction and an aldolase-catalyzed aldol addition reaction enables direct access to a wide range of carbohydrate derivatives containing up to four new hydroxymethylene stereocenters.