CAS: 705-31-7; 4-(Trifluoromethyl)Phenylacetylene

上下游产品

CAS号40230-95-3 三甲基((4-(三氟甲基)苯基... | CAS号402-43-7 对溴三氟甲苯 | CAS号455-13-0 4-碘三氟甲苯 | CAS号1066-54-2 三甲基硅基乙炔 | CAS号4298-52-6 2-乙炔噻吩 | CAS号89619-12-5 Benzene, 1-(1,2... | CAS号118527-34-7 1-(2,2-dichloro... | CAS号131356-53-1 1-(2,2-dibromoe... | CAS号455-19-6 对三氟甲基苯甲醛 | CAS号455-24-3 4-三氟甲基苯甲酸 | CAS号402-50-6 4-(三氟甲基)苯乙烯 | CAS号2062-26-2 反式-2-三氟甲基肉桂酸 | CAS号709-63-7 4'-(三氟甲基)苯乙酮 | CAS号337510-18-6 (4-TRIFLUOROMET... | CAS号243971-02-0 2-[4-(Trifluoro... | CAS号119757-51-6 1,2-双(4-(三氟甲基)苯基)炔 | CAS号886-66-8 1,4-二苯基丁二炔

4-三氟甲基苯基溴化镁置于氢氧化钾,Potassium Hydrogensulfate体系中,化学反应生成 4-乙炔基-α,α,α-三氟甲苯
参考文献:A New Method Of Evaluating Ortho σ-Constants
标题:A New Method Of Evaluating Ortho σ-Constants
摘要:
DOI:10.1021/ja00904A042

专利信息

专利号:US-8835658-B2
优先权日:2012-12-28
标 题:Asymmetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities
发明人：CHAN ALBERT SUN-CHI; FAN BAOMIN; WANG JUN; LIN CHENGYUAN; HUANG CHAO; YANG QINGJING; XU JIANBIN; BIAN ZHAOXIANG; LU AIPING; HU JUN
权利人:UNIV HONG KONG BAPTIST; UNIV YUNNAN NATIONALITIES
摘要:The present invention relates to a type of norcantharidin analogues and a method to synthesis such norcantharidin analogues by transition metal-catalyzed alkynylation of 7-oxabenzonorbornadienes. The present invention also relates to the use of such norcantharidin analogues in manufacture of a medicament for the treatment of cancer tumors.

专利号:US-8420812-B2
优先权日:2007-07-03
标题:Process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates
发明人：RKYEK OMAR; NAZARE MARC; LINDENSCHMIDT ANDREAS; ALONSO JORGE; URMANN MATTHIAS; HALLAND NIS
权利人:RKYEK OMAR; NAZARE MARC; LINDENSCHMIDT ANDREAS; ALONSO JORGE; URMANN MATTHIAS; HALLAND NIS; SANOFI SA
摘要:A process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates n The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), n nwherein D, J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process of heteroaryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional heteroaryl-1-alkynes of the formula I.

专利号:US-2022048879-A1
优先权日:2020-08-13
标 题:Synthesis of small molecules inspired by Phomoxanthone A
发明人：ALI RAMEEZ; MATTSON ANITA
权利人:WORCESTER POLYTECH INST
摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

专利号:WO-03061385-A1
优先权日:2002-01-17
标题:Tricyclic nucleoside library compounds, synthesis, and use as antiviral agents
发明人：AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC
权利人:RIBAPHARM INC; AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC
摘要:Tricyclic nucleoside libraries and library compounds are prepared using combinatorial chemistry and non-combinatorial chemistry methods. Contemplated library compounds are particularly useful in inhibition of viral propagation, and particularly of viral propagation of the HCV virus.

专利号:US-2014187801-A1
优先权日:2012-12-28
标题:Asymetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities

专利号:CN-113582797-B
优先权日:2021-08-17
标 题:A method of copper-catalyzed synthesis of trifluoromethyl-1,3-enyne compounds