CAS: 53427-65-9; 2-(1,4-Diazepan-1-yl)Ethan-1-Ol

该化合物其结构特征为该化合物其结构特征为1,4-二乙烷环,附于乙醇混合物,该化合物的颜色无色可粉黄黄色液体或固体,视其纯度和形态而定;在水和各种有机溶剂中可溶解,使其具有多种用途;二氮环的存在有助于其潜在的生物活动,因为含有氮乙酸循环的化合物往往具有药理特性;分子乙醇部分的氢氧基化合物组(OH)增强了其反应性和形成氢结的能力,可影响其在生物系统中的相互作用;此外,2-(1,4-diazepan-1-yl)乙醇可作为合成药物化学和药物开发中较复杂的分子的建筑块块;应参考安全数据,以便处理和使用,如任何化学物质一样,确保采取适当的预防措施.

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606931-01-5 927802-38-8 1235440-88-6

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上下游产品

oxirane 1,4-Diazacycloheptane N,N'-Di(phenylsulphonyl)hexahydro-1,4-diazepin 1,5-diaza-bicyclo[3.2.2]nonane N-cyclopropyl-3-(2-(cyclopropylmethyl)-4-((4-(2-hydroxyethyl)-1,4-diazepan-1-yl)methyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)-5-fluoro-4-methylbenzamide 4-((6-(5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-2-(cyclopropylmethyl)-1-oxo-1,2-dihydroisoquinolin-4-yl)methyl)-1-(2-hydroxyethyl)-1,4-diazepane 1-oxide 2-[4-(4-nitrophenyl)-[1,4]diazepan-1-yl]ethanol

合成工艺路线路线简述

    📜六氢-1,4-二苯磺酰基-1H-1,4-二氮杂卓置于甲醇,硫酸体系中,化学反应生成 2-(1,4-二叠氮烷-1-基)乙酮
    参考文献:1,4-Diazabicyclo[2.2.2]octanes And 1,5-Diazabicyclo[3.2.2]Nonanes From Piperazines And Homopiperazines
    标题:1,4-Diazabicyclo[2.2.2]octanes And 1,5-Diazabicyclo[3.2.2]Nonanes From Piperazines And Homopiperazines
    摘要:
    DOI:10.1021/ja01633A057

    海关参考信息

    专利信息


    专利号:US-9562037-B2
    优先权日:2014-02-26
    标题:Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents
    发明人:CHOW LARRY MING-CHEUNG; CHAN WILLIAM TAK HANG; CHAN KIN-FAI; WONG IRIS LAI KING; KAN WING-YIU
    权利人:UNIV HONG KONG POLYTECHNIC
    摘要:The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.

    专利号:US-10111854-B2
    优先权日:2014-02-26
    标题 :Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents
    发明人:CHOW LARRY MING-CHEUNG; Chan Tak Hang William; CHAN KIN-FAI; WONG IRIS LAI KING; KAN WING-YIU
    权利人:UNIV HONG KONG POLYTECHNIC
    摘要:The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.

    专利号:US-7235645-B2
    优先权日:2004-07-23
    标 题 :Cationic azo monomers or symmetric dimers, preparation thereof, compositions comprising same and process for dyeing keratin fibers
    发明人:GREAVES ANDREW; BARIL BERANGERE
    权利人:OREAL
    摘要:Disclosed herein are compounds of formulae (I) and (II) below, and also to processes for the synthesis thereof: n nAlso disclosed herein are dye compositions comprising said compounds, as cationic direct dyes, and methods for dyeing keratin fibers, for example, human keratin fibers, using these compositions.

    专利号:US-2017143665-A1
    优先权日:2014-02-26
    标题:Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents

    专利号:US-2015239870-A1
    优先权日:2014-02-26
    标题:Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents

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