CAS: 2222755-14-6; 4-(5-(6-((6-Methoxypyridin-3-yl)Methyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-yl)Pyrazin-2-yl)-6-(((R)-Morpholin-2-yl)Methoxy)Pyrazolo[1,5-A]Pyridine-3-Carbonitrile
- 英文名称4-(5-(6-((6-Methoxypyridin-3-yl)Methyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-yl)Pyrazin-2-yl)-6-(((R)-Morpholin-2-yl)Methoxy)Pyrazolo[1,5-A]Pyridine-3-Carbonitrile
- 中文名称塞尔帕替尼
- IUPAC名称4-(5-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyrazin-2-yl)-6-(((R)-morpholin-2-yl)methoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile
- CAS编号2222755-14-6
- MFCD编号:MFCD32062760
- FDA UNII编号:SM0SJ89UOO
- 分子式:C29H31N9O3分子量:553.61
- 产品CID: 1150610
- 产品分类医药中间体 → 原料药中间体
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合成工艺路线路线简述
海关参考信息
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2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
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主要参考文献
1: Russo A, Lopes AR, McCusker MG, Garrigues SG, Ricciardi GR, Arensmeyer KE, Scilla KA, Mehra R, Rolfo C. New Targets in Lung Cancer (Excluding EGFR, ALK, ROS1). Curr Oncol Rep. 2020 Apr 16;22(5):48. doi: 10.1007/s11912-020-00909-8. 15(4):541-549. doi: 10.1016/j.jtho.2020.01.006. Epub 2020 Jan 24. 16(2):77-78. doi: 10.1038/s41574-019-0307-2. 25(12):1839-1842. doi: 10.1038/s41591-019-0653-6. Epub 2019 Nov 25.
7: Li AY, McCusker MG, Russo A, Scilla KA, Gittens A, Arensmeyer K, Mehra R, Adamo V, Rolfo C. RET fusions in solid tumors. Cancer Treat Rev. 2019 Dec;81:101911. doi: 10.1016/j.ctrv.2019.101911. Epub 2019 Oct 30. 29(11):1704-1707. doi: 10.1089/thy.2019.0041.
12:7857-7864. doi: 10.2147/OTT.S171665.
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