CAS: 18163-47-8; (Iodoethynyl)Trimethylsilane

该化合物是一种有机碘化合物,其特征为:碘原子和三甲基硅组都同时附着在乙炔脊上;其分子结构具有终端烷基,有助于其再活动,特别是在核循环替代反应中;三甲基硅组增强了该化合物在有机溶剂中的稳定性和溶性,使其在各种合成应用中有用;该化合物一般没有色素,可变成黄色的液体,其沸点相对较低,表明其挥发性;该化合物对湿气和空气敏感,需要在惰性条件下小心处理和储存;碘原子的存在使其在有机合成中成为有价值的中间体,特别是在形成碳-碳联结和制作更复杂的有机分子方面;与许多有机碘化合物一样,该化合物可能表现出毒性,应在通风良好的实验室环境中以适当的安全防范措施加以处理.

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1066-54-2

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CAS号1066-54-2 三甲基硅基乙炔 | CAS号14630-40-1 双(三甲基硅基)乙炔 | CAS号75-77-4 三甲基氯硅烷 | CAS号74-86-2 乙炔 | CAS号4526-07-2 1,4-双(三甲硅基)-1,3-丁二炔 | CAS号618-91-7 3-碘苯甲酸甲酯 | CAS号619-44-3 4-碘苯甲酸甲酯 | CAS号232264-73-2 11-oxa-tricyclo... | CAS号2170-06-1 1-苯基-2-(三甲基硅)乙炔 | CAS号78389-99-8 trimethyl(5-met... | CAS号99299-72-6 2-Ethynyl-6-met... | CAS号56904-79-1 4-ethyl°Ct-3-en... | CAS号56053-89-5 5-trimethylsily...

合成工艺路线路线简述

    📜二(三甲基甲硅烷基)乙炔置于一氯化碘体系中,用 四氯化碳 用作溶剂,以90%的收率获得1-碘-2-三甲基硅基乙炔
    参考文献:Halogenation Of Alkynes And Alkynylsilanes
    标题:Halogenation Of Alkynes And Alkynylsilanes
    摘要:
    Doi:10.1016/0022-328X(89)87090-1

    海关参考信息

    专利信息


    专利号:US-5338865-A
    优先权日:1992-03-12
    标 题 :Synthesis of halichondrin B and norhalichondrin B
    发明人:KISHI YOSHITO; FANG FRANCIS; FORSYTH CRAIG J; SCOLA PAULA M; YOON SUK KYOON
    权利人:HARVARD COLLEGE
    摘要:Novel chemical compounds that can be used to synthesize halichondrin B and norhalichondrin B, and related derivatives, are described. The synthesis of halichondrin B and norhalichondrin B from these compounds also is described.

    专利号:US-7232842-B2
    优先权日:2003-01-10
    标题:Kinase inhibitors and associated pharmaceutical compositions and methods of use
    发明人:WENDER PAUL A; SCANIO MARC J
    权利人:UNIV LELAND STANFORD JUNIOR
    摘要:The invention provides novel compounds useful as kinase inhibitors or as starting materials And/or intermediates in the synthesis of compounds useful as kinase inhibitors. The compounds have The general structure of formula (I) n nwherein A is a 3- to 8-membered ring, optionally substituted and/or heteroatom-containing, and R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , X, Y, Z, p, and q are as defined herein. The compounds may also be in the form of a salt, ester, amide, or other analog. In preferred compounds, A is a 5- to 8-membered ring, R 1 is hydrogen, q is a bond, X is N, Y is Câ•?O, Z is N, R 2 contains a terminal amino moiety, p is 1, and R 3 and R 4 are linked to form a pyrrole ring fused to a second cyclic group. Pharmaceutical compositions and methods for using the compounds are also provided.

    专利号:US-2006223947-A1
    优先权日:2005-04-05
    标题 :Chemical synthesis of polymeric nanomaterials and carbon nanomaterials
    发明人:OLESIK SUSAN V; DING LUNHAN
    权利人:UNIV OHIO STATE RES FOUND
    摘要:A high yield method for chemically synthesizing low polydispersivity carbon microspheres, nanospheres, nanocrystals, nanotubes, or nanofibers comprising dispersing a self-polymerizing end-capped polyyne in a solvent; heating the dispersed self-polymerizing end-capped tetrayne to form a polymeric material selected from the group consisting of polymer microspheres, polymer nanospheres, polymer nanocrystals, polymer nanotubes, and polymer nanofibers; and pyrolyzing the polymeric material to form a carbon material selected from the group consisting of carbon microspheres, carbon nanospheres, carbon nanocrystals carbon nanotubes, and carbon nanofibers, wherein the polydispersivity is less than 2.

    专利号:US-5436238-A
    优先权日:1992-03-12
    标 题:Halichondrins and related compounds
    发明人:KISHI YOSHITO; FANG FRANCIS; FORSYTH CRAIG J; SCOLA PAULA M; YOON SUK KYOON
    权利人:HARVARD COLLEGE
    摘要:Novel chemical compounds that can be used to synthesize halichondrin B and norhalichondrin B, and related derivatives. The total synthesis of halichondrin B and norhalichondrin B is also disclosed.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Elodie E Marlier, Et Al. Synthesis And Reactivity Of An Isolable Cobalt(I) Complex Containing A β-Diketiminate-Based Acyclic Tetradentate Ligand. Inorg Chem. 2012 Feb 20;51(4):2079-85.

    合成参考文献


    摘要:Udmark, J.; Brøndsted Nielsen, M., Science of Synthesis Knowledge Updates, (2014) 3, 360.
    摘要:Huy, P.; Czekelius, C., Science of Synthesis Knowledge Updates, (2019) 2, 172.
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