CAS: 126778-79-8; (4S,4As,6S,6Ar,9R,11As,11Bs)-6-Hydroxy-4,11B-Dimethyl-8-Methylenetetradecahydro-6A,9-Methanocyclohepta[a]Naphthalene-4-Carboxylic Acid

该化合物是一种二类化合物,其特点是其独特的甲状腺骨骼,C-7位置上有一个氢氧化物组,C-18位置上有一个碳球酸.这种结构配置具有独特的化学和生物特性,使其成为有机合成和制药研究的宝贵中间体.其硬性四环框架和功能组为衍生提供了机会,有利于医药化学的应用,特别是在生物活性天然产品研究中的应用.该化合物的立体化学特性(4β,7β)进一步增强了其在立体选择性反应和机械学调查中的效用.高纯度和明确界定的结构确保研究应用的再生.

英文名称(4S,4As,6S,6Ar,9R,11As,11Bs)-6-Hydroxy-4,11B-Dimethyl-8-Methylenetetradecahydro-6A,9-Methanocyclohepta[a]Naphthalene-4-Carboxylic Acid
中文名称(4β,7BETA)-7-羟基贝壳杉-16-烯-18-酸
IUPAC名称(4S,4aS,6S,6aR,9R,11aS,11bS)-6-hydroxy-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid
其它别名7β-Hydroxykaur-16-En-19-Oic Acid; Sventenic Acid; (4Beta,7Beta)-7-Hydroxykaur-16-En-18-Oic Acid; Kaur-16-En-18-Oic Acid, 7-Hydroxy-, (4β,7β)-
CAS编号126778-79-8
MFCD编号:MFCD32645057
分子式:C20H30O3分子量:318.46
产品CID: 424310
产品分类天然产物 → 萜类

相似结构搜索
InChIKey: KMLXVEXJZSTMBV-HNFSSWLOSA-N
InChI=1S/C20H30O3/c1-12-10-20-11-13(12)5-6-14(20)18(2)7-4-8-19(3,17(22)23)15(18)9-16(20)21/h13-16,21H,1,4-11H2,2-3H3,(H,22,23)/t13-,14+,15+,16+,18+,19+,20+/m1/s1
计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数1.0

MSDS等安全信息

危险描述H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
防范说明P264+P280+P305+P351+P338+P337+P313
危险品标志Xi
安全声明H303+H313+H333

上下游产品

Epicandicandiol 7β-monoacetate kaur-16-en-18-oic acid

合成工艺路线路线简述

📜Kaur-16-En-18-Oic Acid置于rhizopus Oligosporus体系中,用乙醇用作溶剂,化学反应 168.0H,以7.8%的收率获得sventenic Acid; (4Beta,7Beta)-7-羟基贝壳杉-16-烯-18-酸
参考文献:Biotransformation Of Ent-Kaur-16-En-19-Oic Acid By Absidia Blakesleeana And Rhizopus Oligosporus
标题:Biotransformation Of Ent-Kaur-16-En-19-Oic Acid By Absidia Blakesleeana And Rhizopus Oligosporus
摘要:Biotransformation Of Ent-Kaur-16-En-19-Oic Acid Was Carried Out With Absidia Blakesleeana And Rhizopus Oligosporus. Absidia Blakesleeana Produced Two Novel Metabolites,Ent-(7,9)-Dihydroxy-Kaur-16-En-19-Oic Acid And Ent-(1,7)-Dihydroxy-Kaur-16-En-19-Oic Acid,Together With Three Known Compounds: Ent-7-Hydroxy-Kaur-16-En-19-Oic Acid,Ent-(7,11)-Dihydroxy-Kaur-16-En-19-Oic Acid And Ent-(7,13)-Dihydroxy-Kaur-16-En-19-Oic Acid. The Ent-7-Hydroxy-Kaur-16-En-19-Oic Acid And Ent-(7,9)-Dihydroxy-Kaur-16-En-19-Oic Acid Were Obtained From R. Oligosporus. The Structures Were Established By Spectroscopic Techniques And X-Ray Crystallography.
Doi:10.1080/14786410902941139