CAS: 849925-22-0; (S)-1-{(Sp)-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocenyl}Ethylbis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphine
该化合物是复杂的有机金属化合物化合物.它有一个环开天框架,由五人组成碳环,与铁协调,表明其在催化中或作为各种化学反应的前体的潜在用途.磷离心和磷,特别是含有三氟甲基混合物,表明其电子特性和消毒效应得到加强,可能影响化合物的再活性和稳定性.这种物质可能具有独特的特性,如有机溶剂中的溶解性,具体的再活性模式和有机合成或材料科学中的潜在应用.其复杂结构及其多种功能组的存在使其成为化学和化学研究的一个主题.
- 英文名称(S)-1-{(Sp)-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocenyl}Ethylbis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphine
- 中文名称铁(2+)1-[(1R)-1-{双[3,5-双(三氟甲基)苯基]膦基}乙基]-2-[2-(二环己基膦基)苯基]环戊二烯-1-基环戊二烯-1-基(1/1/1)
- 其它别名(S)-1-[(S)-2-(2'-Dicyclohexylphosphino-Phenyl)-Ferrocenyl]-Ethyl-Di-(Bis-(3,5-Trifluoromethyl)-Phenyl)Phosphine; (S)-1-{(S)-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocenyl}Ethylbis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphine; (S,S)-1-{1-[bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]Ethyl}-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocene (Acc To Cas); (S)-1-{(Sp)-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocenyl}Ethylbis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphine; (S)-1-{(S)-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocenyl}Ethylbis[3,5-Bis(Triflu; (S)-1-[(S)-1-[bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino] Ethyl]-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocene; (S)-1-[(Sp)-1-[bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]Ethyl]-2-[2-(Dicyclohexylphosphino)Phenyl]Ferrocene
- CAS编号849925-22-0
- MFCD编号:MFCD08561127
- 分子式:C41H39F12P2.C5H5.Fe分子量:942.623
- 产品CID: 1841918
- 产品分类化学试剂 → 有机试剂 → 膦配体
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2903399090-其他无环烃卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9403766-B2
优先权日:2008-01-17
标 题:Intermediates for producing NEP inhibitors or prodrugs thereof
发明人：HOOK DAVID; RISS BERNARD; KAUFMANN DANIEL; NAPP MATTHIAS; BAPPERT ERHARD; POLLEUX PHILIPPE; MEDLOCK JONATHAN; ZANOTTI-GEROSA ANTONIO
权利人:HOOK DAVID; RISS BERNARD; KAUFMANN DANIEL; NAPP MATTHIAS; BAPPERT ERHARD; POLLEUX PHILIPPE; MEDLOCK JONATHAN; ZANOTTI-GEROSA ANTONIO; NOVARTIS AG
摘要:The invention relates to a new process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according to the present invention, are ultimately related to the synthesis of intermediates to prepare the above NEP inhibitors, namely compounds according to formula (1), or salt thereof, n nwherein R1 and R2 are, independently of each other, hydrogen or a nitrogen protecting group, and R3 is a carboxyl group or an ester group, preferably carboxyl group or alkyl ester.
