CAS: 83-01-2; Diphenylcarbamoyl Chloride

上下游产品

CAS号32315-10-9 三光气 | CAS号122-39-4 二苯胺 | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号116-16-5 六氯丙酮 | CAS号108-86-1 溴苯 | CAS号75-44-5 光气 | CAS号10509-95-2 phenyl-carbonim... | CAS号622-44-6 二氯代苯胩 | CAS号873989-92-5 diphenyl-carbam... | CAS号607-00-1 N,N-二苯基甲酰胺 | CAS号122-39-4 二苯胺 | CAS号20619-23-2 N,N-diphenylpro... | CAS号103-72-0 异硫氰酸苯酯 | CAS号611-01-8 2,4-二甲基苯甲酸 | CAS号2990-01-4 Urea,N,N-dimeth... | CAS号24293-93-4 1,3-双(1,3,3-三甲基... | CAS号603-52-1 N,N-二苯基氨基甲酸乙酯 | CAS号5400-75-9 5-甲基-1H-苯并[d]咪唑...

N-Phenyl-Chlor-Formimidsaeurephenylester 反应生成 二苯氨基甲酰氯
参考文献:Kuehle,E. Et Al.,Angewandte Chemie,1969,Vol. 81,P. 18-32
标题:Kuehle,E. Et Al.,Angewandte Chemie,1969,Vol. 81,P. 18-32

专利信息

专利号:US-8273790-B2
优先权日:2005-01-14
标 题:Exo-selective synthesis of himbacine analogs
发明人：THIRUVENGADAM TIRUVETTIPURAM K; SUDHAKAR ANANTHA; LIM NGIAP KIE; KWOK DAW-IONG; WU GEORGE G; WANG TAO; HUANG MINGSHENG; GREEN MICHAEL D
权利人:THIRUVENGADAM TIRUVETTIPURAM K; SUDHAKAR ANANTHA; LIM NGIAP KIE; KWOK DAW-IONG; WU GEORGE G; WANG TAO; HUANG MINGSHENG; GREEN MICHAEL D; SCHERING CORP
摘要:This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. The compounds produced thereby are useful as thrombin receptor antagonists. The chemistry disclosed herein is exemplified in the following synthesis sequence:

专利号:US-3933830-A
优先权日:1974-09-10
标 题 :Process for the synthesis of 4-(2-pyridylamido ethyl) piperidines
发明人：BARTH WAYNE E; KUHLA DONALD E
权利人:PFIZER
摘要:Disclosed herein is an improved process for the preparation of known hypoglycemic piperidinesulfamylureas of the structure ##EQU1## wherein R is selected from the group consisting of 3-(2-methoxy)pyridyl, 3-(2-ethoxy)pyridyl and 2-(4-chloro)pyridyl and R' is selected from the group consisting of bicyclo[2.2.1]hept-5-en-2-yl-endo-methyl, bicyclo[2.2.1]hept-2-yl-endo-methyl, 7-oxabicyclo[2.2.1]hept-2-yl-methyl, 1-adamantyl and cycloalkyl having from five to eight carbon atoms. n Said process comprises contacting 4-(2-pyridyl-amidoethyl) piperidine of the structure ##EQU2## with substantially one equivalent of sulfamide thereby exclusively sulfonating the piperidine nitrogen atom. Said 4-(2-pyridylamidoethyl)piperidines from the corresponding 4-(2-pyridylamidoethyl) pyridines by selectively activating the more basic nitrogen atom of said pyridine compound either by N-alkylation or by contact with acid and then exclusively reducing the activated pyridine ring with either hydrogen alone or in combination with a metal hydride. Said 4-(2-pyridylamidoethyl)pyridines are produced by contacting 4-(2-aminoethyl)pyridine with a pyridyl acid chloride of the formula R(C=O)Cl. The piperidine sulfonamides produced by the process of the instant invention are converted to the desired hypoglycemic agent by methods well-known to those skilled in the art. n The 4-(2-pyridylamidoethyl)pyridines and piperidines of the instant invention are themselves novel compounds useful as intermediates in the synthesis of piperidine sulfamylurea hypoglycemic agents.

专利号:WO-9845231-A1
优先权日:1997-04-09
标题:Supports for solid phase synthesis
发明人：SHAO HUI; CASTELHANO ARLINDO L
权利人:CADUS PHARMACEUTICAL CORP
摘要:Supports for solid-phase synthesis are disclosed. The supports include a phenol or thiophenol linker moiety. A substrate compound can be immobilized to the support through the linker moiety. The supports are suitable for combinatorial synthesis, including synthesis of combinatorial libraries.

专利号:WO-2024185775-A1
优先权日:2023-03-06
标 题:Long-chain alkenyloxy–substituted benzoyl derivative and oligonucleotide synthesis method using same
发明人：OKADA YOHEI; INANAGA KAZATO; SHOJI Yukiya; MIZUFUNE HIDEYA; SUDO TATSUYA; ADACHI Sota; HOSOI Kazushi
权利人:SPERA PHARMA INC; TOKYO UNIV OF AGRICULTURE AND TECHNOLOGY
摘要:The purpose of the present invention is to provide a novel pseudo–solid phase protecting group that can be used in liquid-phase oligonucleotide synthesis. The purpose of the present invention is also to provide an oligonucleotide synthesis method that uses a novel pseudo–solid phase protecting group.　The present invention provides a compound represented by formula (1) (in which R represents a C14–60 alkenyl group, n represents 2 or 3, m represents 0 or 1, p represents 1 or 2, X represents C, N, O, or S, Y represents a single bond or B(CH 2 ) t * or may form a ring with X, and Z represents a single bond or (CH 2 ) s (s being an integer from 1 to 5)). The present invention also provides an oligonucleotide production method that uses the compound.

专利号:US-10760063-B2
优先权日:2014-10-20
标 题:Modified template-independent enzymes for polydeoxynucleotide synthesis
发明人：EFCAVITCH J WILLIAM; TUBBS JULIE L; SINHA PREM; STEC BOGUSLAW
权利人:MOLECULAR ASSEMBLIES INC
摘要:The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template. The invention further includes the identified polymerases, and methods of using the polymerases for de novo synthesis of predetermined oligonucleotide sequences.

专利号:WO-2022220019-A1
优先权日:2021-04-16
标题 :Long-chain dna synthesis using non-natural base
发明人：MASAKI YOSHIAKI
权利人:TOKYO INST TECH
摘要:The purpose of the present invention is to provide a method for synthesizing a long-chain nucleic acid (particularly DNA) with high accuracy. The present invention provides a method for synthesizing a long-chain nucleic acid, the method comprising using: (i) a nucleoside-3'-O-phosphoramidite derivative having a non-natural nucleic acid base; or (ii) a nucleoside-3'-O-phosphoramidite derivative having a non-natural nucleic acid base and a nucleoside-3'-O-phosphoramidite derivative having a natural nucleic acid base in the chemical synthesis of a nucleic acid based on the phosphoramidite method.