CAS: 7784-54-5; A-D-Glucosamine Pentaacetate
该化合物是一种碳水化合物化合物化合物,其特点是其乙基功能组,其特性为乙基苯基化合物,该物质具有一种六人组成的循环甘基糖结构,在乙基氨基组所在的2个位置和乙基氨基组所在的1,3,4和6个位置作了具体修改,这些修改加强了其溶性与再活性,使其在各种生物化学应用中有用,包括作为凝聚反应和更为复杂的碳水化合物合成的建筑块,多种乙基酰基化合物的存在有助于其稳定性并影响其与生物系统的互动.这种化合物一般为白色至表面不白,在极地溶剂中可溶解.其应用可能扩大到药物,生物化学和材料科学,从而可以进一步转化化学前体.
- 英文名称A-D-Glucosamine Pentaacetate
- 中文名称α-D-氨基葡萄糖五乙酸盐
- IUPAC名称(2R,3R,4R,5S,6R)-3-acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl triacetate
- 其它别名α-D-葡萄糖胺五乙酸酯; 2-Acetamido-1,3,4,6-Tetra-O-Acetyl-2-Deoxy-α-D-Glucopyranose
- CAS编号7784-54-5
- MFCD编号:MFCD00065051
- EINECS号:232-071-0
- 分子式:C16H23NO10分子量:389.35
- 产品CID: 1773212
- 产品分类有机原料→生命科学→糖类
相似化合物
76375-61-6 7772-79-4 7772-94-3物理性质
上下游产品
β-D-葡萄糖胺五乙酸酯 2-Acetamido-1,3,4,6-Tetra-O-Acetyl-2-Deoxy-β-D-Glucopyranose 7772-79-4Methyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-α-D-Glucopyranoside 2595-39-3
Methyl N-Acetyl-D-Glucosamine
D-Glcnac 7512-17-6
N-Acetylglucosamine
2-乙酰氨基-2-脱氧-Alpha-D-吡喃糖 N-Acetyl-D-Glucosamine 10036-64-3
2-乙酰氨基-2-脱氧-Beta-D-吡喃葡萄糖胺 D-N-Acetylglucosamine 14131-68-1
2-乙酰氨基-3,4,6-三-O-乙酰-2-脱氧-α-D-吡喃葡萄糖酰基氯 Acetic Acid (2R,3S,4R,5R,6R)-3-Acetoxy-2-Acetoxymethyl-5-Acetylamino-6-Chloro-Tetrahydro-Pyran-4-Yl Ester 3068-34-6
合成工艺路线路线简述
📜D-Glcnac置于dowex 50W-X8 Cation Exchange Resin,硫酸体系中,用 溶剂黄146 作为反应溶剂,化学反应 77.0H,反应生成 A-D-氨基葡萄糖五乙酸盐
参考文献:Preparative Routes To Methyl 2-Acetamido-2,6-Dideoxy-α-D-Glucopyranoside
标题:Preparative Routes To Methyl 2-Acetamido-2,6-Dideoxy-α-D-Glucopyranoside
摘要:
DOI:10.1016/0008-6215(83)84058-0
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5756712-A
优先权日:1997-01-23
标题:Peptidodisaccharides as oligosaccharide mimetics
发明人：SABESAN SUBRAMANIAM
权利人:DU PONT
摘要:Methods are provided to replace the ether oxygen linkage of oligosaccharides with a peptide link, -NHC(O)-, where the nitrogen atom is linked to the anomeric carbon atom of the sugar. A new family of building blocks for combinational synthesis, peptidodisaccharides, is provided containing the peptide linkage. Synthesis is more facile than with the oxygen-linked carbohydrates; the resulting compounds are expected to be more stable to enzymatic and chemical hydrolysis and to be amenable to automated synthesis.
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of 5-Fluoro N-Acetylglucosamine Glycosides And Pyrophosphates Via Epoxide Fluoridolysis: Versatile Reagents For The Study Of Glycoconjugate Biochemistry作者:Matthew C. T. Hartman,James K. Coward |发布日期:2002.8.1
摘要:Catalysis Via Stabilization Of Positive Charges On Or Near The C-1, C-4, C-5, Or C-6 Positions. Substrate Analogues Differing Only In The Substitution Of A Fluorine For The Axial C-5 Hydrogen Would Possess Reduced Electron Density At These Positions And Could Be Useful Mechanistic Probes Of These Enzymes. Introduction Of This 5-Fluoro Substituent After Radical Halogenation Was Problematic Because Of The Incompatibility
合成参考文献
摘要:Kryczka, B.; Lewkowski, J.; Zawisza, A., Science of Synthesis, (2007) 29, 998.
摘要:Kryczka, B.; Lewkowski, J.; Zawisza, A., Science of Synthesis, (2007) 29, 990.
摘要:Montforts, F.-P.; Osmers, M.; Azov, V. A., Science of Synthesis, (2009) 40, 219.
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