CAS: 5422-34-4; 2-Hydroxy-N-(2-Hydroxyethyl)Propanamide

该化合物是一种氢氧化亚胺化合物,其特征是其双重氢氧基组,这提高了其在极地溶剂和水中的溶性.这一结构赋予了适合聚合物修改,交叉连接和有机合成的一个构件应用的回活动性.该化合物的双功能性允许多功能衍生,使其在需要水利和温和再活性的地方可用于涂层,粘合剂和个人护理配方. 它在典型的加工条件下的稳定性以及与其他氢氧反应系统的兼容性进一步扩大了其在工业和特殊化学应用中的实用性.

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3586-25-2 855634-55-8 5422-34-4

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    📜乳酸甲酯,C.I.酸性橙108 反应生成 乳酰胺 Mea
    参考文献:Preparation Of N-Substituted Lactamides By Aminolysis Of Methyl Lactate2,3
    标题:Preparation Of N-Substituted Lactamides By Aminolysis Of Methyl Lactate2,3
    摘要:
    DOI:10.1021/jo01148A013

    海关参考信息

    专利信息


    专利号:US-4627968-A
    优先权日:1984-09-10
    标 题 :Synthesis of crystalline aluminosilicate with alkylurea or alkylthiourea
    发明人:KAI TADASHI
    权利人:ASAHI CHEMICAL IND
    摘要:In the synthesis of a crystalline aluminosilicate by heating an aqueous mixture containing a silica source, an alumina source and an alkali metal source, at least one compound selected from lower alkylureas and lower alkylthioureas is permitted to co-exist with the mixture.

    专利号:US-2005069551-A1
    优先权日:2002-03-08
    标题 :Cytotoxic compound-protein conjugates as suppressors of tumor growth and angiogenesis
    发明人:SHOJI MAMORU; SNYDER JAMES P; LIOTTA DENNIS C; SUN AIMING
    权利人:UNIV EMORY
    摘要:Compositions and methods are provided for delivering cytotoxic compounds, such as natural curcumoids and synthetic curcumin analogs, specifically to cancer cells and to blood vessels that nourish solid tumors. The compositions include a cytotoxic drug tethered to a protein, such as factor VIIa, which can bind with high affinity to a receptor, such as tissue factor, expressed on the surface of cancer cells and vascular endothelial cells within the tumor microenvironment. Upon binding, the drug-protein-receptor complex is endocytosed and the drug is subsequently liberated inside the target cell via proteolytic cleavage. The compositions and methods may increase the efficacy of the cytotoxic agets and decrease their side effects by delivering the agents to specific target cells, such as cancer cells, vascular endothelial cells in a tumor, and metastatic foci anywhere in the body, providing the target cells express surface bound tissue factor. Additionally, methods of synthesis of cytotoxic compound-protein conjugates are provided, for example, curcuminoid-tether-linker-factor VIIa composition, as well as pharmaceutically acceptable compositions and methods for delivering a therapeutically-effective amount of a cytotoxic compound-protein conjugate together with one or more pharmaceutically acceptable carriers (additives) and/or diluents to an animal or human patient.

    专利号:US-7598403-B2
    优先权日:2003-05-16
    标 题 :Synthesis of chromanones
    发明人:SALVATORE BRIAN A; SOLIS FERDINAND C
    权利人:UNIV SOUTH CAROLINA RES FOUND
    摘要:Processes for the preparation of biologically active chromanones are disclosed, including processes for the preparation of intermediates useful in the preparation of the biologically active chromanones. The chromanones and the intermediates disclosed herein may be useful for a variety of therapies, including the treatment of various cancers and the treatment of inflammation and inflammation related disorders.

    专利号:US-2019276389-A1
    优先权日:2015-12-18
    标题:Synthesis of aryl cyclohexane ester derivatives useful as sensates in consumer products
    发明人:WOS JOHN AUGUST; YELM KENNETH EDWARD; BUNKE GREGORY MARK; FREDERICK HEATH ALAN; REILLY MICHAEL; HAUGHT JOHN CHRISTIAN; SREEKRISHNA KOTI TATACHAR; LIN YAKANG
    权利人:PROCTER & GAMBLE
    摘要:Personal care compositions, such as oral care and skin care compositions containing a flavor/perfume system comprising one or more coolants. The pleasant cool sensation provided by a coolant is enhanced in terms of quicker onset, greater intensity, impact or longer duration, which improves appeal and acceptability of the compositions to consumers.

    专利号:US-2007203214-A1
    优先权日:2003-05-16
    标 题 :Synthesis Of Chromanones

    专利号:AU-2016371908-A1
    优先权日:2015-12-18
    标题 :Synthesis of cyclohexane ester derivatives useful as sensates in consumer products

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Arzneimittel-Forschung. Drug Research., 28(1579), 1978 []
    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 34(Suppl.1):18-34, 2015
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