专利号:US-4970309-A 优先权日:1985-12-16 标题:Synthesis of thiolactones 发明人:KING PATRICK F 权利人:POLAROID CORP 摘要:This invention relates to a novel method of synthesizing di- and triarylmethane dye precursor compounds possessing a thiolactone ring-closing moiety, from the corresponding lactones.
专利号:US-2024228986-A1 优先权日:2021-05-14 标题 :Engineered cells, enzymes, and methods for producing cannabinoids 发明人:KAMBOURAKIS SPIROS; KEUL NICHOLAS DONALD; KOMOR RUSSELL SCOTT; URANO JUN; CAIAZZA NICKY CHRISTOPHER 权利人:CELLIBRE INC 摘要:Disclosed herein are novel CBGA and CBGVA synthases and methods for improvement of their overall activities for the synthesis of CBGA and CBGVA from their respective precursors, olivetolic acid (OA) or divarinic acid (DVA) and GPP. Also disclosed are fusion proteins to enhance synthesis of CBGA and CBGVA. The methods described herein also increase the titer and the purity of CBGA and CBGVA made by a cell by 1) decreasing the formation of byproducts FCBGA and FCBGVA that are synthesized from the respective prenylation of OA and DVA with FPP, and/or 2) increasing the intracellular availability of OA and DVA.
专利号:US-8273403-B2 优先权日:2002-05-10 标题 :Generation of surface coating diversity 发明人:BARDEN MICHAEL C; KAMBOURIS PETER A 权利人:BARDEN MICHAEL C; KAMBOURIS PETER A; BIO LAYER PTY LTD 摘要:This invention relates to a surface discovery system and high-throughput combinatorial synthesis methods for generating large numbers of diverse surface coatings on solid substrates. The system is built upon a synthon which comprises at least three elements: a chemical backbone coating on the solid substrate that comprises a copolymer (B) of at least one passive constituent (P) and at least one active constituent (A); a spacer unit (S) separating the backbone from a functional group; and a functional group (F). The methods comprise the following steps: 1) selecting a plurality of synthons so that each synthon has at least two points of diversity selected from P, A, S and F; 2) applying copolymer B onto a substrate; and 3) attaching a combination of S and F to constituent A of copolymer B. Steps 2) and 3) are performed such that different synthons are generated on localized regions of the substrate.
专利号:WO-2025007156-A2 优先权日:2023-06-30 标 题:Enzymes and methods for the synthesis of bakuchiol and derivatives
专利号:US-7196230-B2 优先权日:2002-03-11 标 题 :Phosoxophite ligands and use thereof in carbonylation processes 发明人:PENG WEI-JUN; BRYANT DAVID ROBERT 权利人:UNION CARBIDE CHEM PLASTIC 摘要:A novel organophosphorus composition and synthesis thereof, the composition being characterized by one phosphite moiety, one phosoxophite moiety, and a plurality of sterically bulky substituents. The novel composition finds utility as a ligand in Group VIII transition metal phosoxophite complex catalysts and complex catalyst precursors that are used in carbonylation processes, preferably, hydroformylation processes. Additionally, there is disclosed a novel method of preparing a phosphoromonochloridite composition that finds utility as a precursor to the novel phosoxophite composition.
专利号:US-9649292-B2 优先权日:2015-07-13 标 题:Method for treating prostate cancer and/or gastrointestinal cancer 发明人:AL-JAROUDI SAID; ALTAF MUHAMMAD; AL-SAADI ABDULAZIZ; ISAB ANVARHUSEIN ABDULKADIR 权利人:UNIV KING FAHD PET & MINERALS 摘要:Gold(III) complexes having mixed ligands as anticancer agents. The gold(III) complexes are coordinated to bidentate ligands having diamino functional groups: a diaminocyclohexane ligand and an ethylenediamine ligand. These complexes can exist in both cis- and trans-configurations. Also described are pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis.
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合成参考文献
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