CAS: 142797-34-0; (2R,3R)-3,5,7-Trihydroxy-2-((2S,3S)-3-(4-Hydroxy-3-Methoxyphenyl)-2-(Hydroxymethyl)-2,3-Dihydrobenzo[b][1,4]Dioxin-6-yl)Chroman-4-One

上下游产品

coniferol taxifolin {3-[(2R,3R)-2-Hydroxymethyl-3-(3-methoxy-4-methoxymethoxy-phenyl)-2,3-dihydro-benzo[1,4]dioxin-6-yl]-oxiranyl}-(2,4,6-tris-methoxymethoxy-phenyl)-methanone 4-hydroxy-3-(methoxymethoxy)benzaldehyde

专利信息

专利号:US-RE40849-E
优先权日:1998-04-30
标题:Method of treatment of glutathione deficient mammals
发明人：KELLER ROBERT H; KIRCHENBAUM DAVID W
权利人:VIT IMMUNE L C
摘要:Glutathione (GSH) is a tripeptide of extreme importance as a catalyst, reductan, and reactant. It can be depleted intracellulary either by forming a direct complex with an electrophilic agent (accomplished investigationally by agents such as bromobenzene or diethyl maleate), by way of inhibition of synthesis, or by subjecting cells to oxidant stress. Most cells, except for epithelia cells, do not have a direct transport capacity for intact GSH. Non-epithelial cells must either transport precursor substrates for GSH synthesis or salvage amino acids from circulating GSH for reuse in intracellular resynthesis. Dietary cysteine is a rate limiting substrate for the synthesis of glutathione and also inhibits GSH efflux. Although GSH is synthesized from precursors in virtually all cells, the liver is the main source of plasma GSH. Protection and support of liver function is paramount to elevating GSH levels. The disclosure is also of a unique combination of nutritional supplements including n-acetyl cysteine, vitamin C, l-glucosamine, n-acetyl d-glucosamine, quercitin, sylimarin, Alpha lipoic acid and high protein, low fat whey that are combined to support various bodily systems involved in glutathione synthesis, reutilization and storage; all intended to elevate glutathione concentration in the mammalian cell.

专利号:EP-4541351-A1
优先权日:2023-10-18
标 题 :Compounds and combination as stimulators of collagen synthesis
发明人：ALBERTÃ? PALMER JUAN JESÚS; STELLA GEORGINA NATALIA; PROHENS LÓPEZ RAFEL; BARRERA BARCELÓ FERNANDO
权利人:CENTER FOR INTELLIGENT RES IN CRYSTAL ENGINEERING S L
摘要:The present disclosure relates to a compound selected from the group consisting of pterostilbene or a cocrystal thereof; silybin or a pharmaceutically acceptable salt of thereof, or any stereoisomer or mixtures of stereoisomers of any of them; a complex of silybin or of any of stereoisomer or mixtures of stereoisomers thereof; or a glycoside of silybin or of any stereoisomer or mixtures of stereoisomers thereof, either for use in the treatment of a disease or disorder mediated by the loss of endogenous type I collagen, or for use in joint functionality improvement, articular disease healing; tendon-bone, bone, and muscle repair improvement; or in wound healing. It also relates to combinations of pterostilbene or a cocrystal thereof, and silybin, particularly addressed to the treatment of a disease or disorder mediated by the loss of endogenous type I collagen, as well as to pharmaceutical compositions and kits containing them, and to the use of the latter in for any one of the mentioned treatments.

专利号:CN-105400843-A
优先权日:2015-11-20
标 题 :A kind of method using laccase to catalyze the synthesis of silibinin

专利号:CN-105400843-B
优先权日:2015-11-20
标 题 :A kind of method using laccase to catalyze the synthesis of silibinin

专利号:CN-105037337-B
优先权日:2015-06-29
标 题:A kind of silybin ether derivative and its synthesis method and application

专利号:CN-105037337-A
优先权日:2015-06-29
标题 :A kind of silybin ether derivative and its synthesis method and application