CAS: 886531-62-0; (2-Phenylpyrimidin-5-yl)Methanol

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85386-14-7 122773-97-1 130161-46-5

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CAS号130161-46-5 2-苯基嘧啶-5-甲醛

📜2-苯基嘧啶-5-甲醛置于甲醇,Sodium Tetrahydroborate体系中,化学反应 2.0H,以65%的收率获得产物5-羟甲基-2-苯基嘧啶
参考文献: Hepatitis B Core Protein Allosteric Modulators[fr] Modulateurs Allostériques Des Protéines Du Noyau De L'Hépatite B
标题: Hepatitis B Core Protein Allosteric Modulators[fr] Modulateurs Allostériques Des Protéines Du Noyau De L'Hépatite B
摘要:摘要 本公开提供了部分具有对乙型肝炎病毒cp具有变构效应的化合物.本文还提供了治疗病毒感染(如乙型肝炎)的方法,包括向需要的患者施用所述化合物.

专利信息

专利号:US-3869456-A
优先权日:1972-03-13
标 题 :Synthesis of 5-pyrimidinecarbinols
发明人：TAYLOR HAROLD M; DAVENPORT JAMES D; HACKLER RONALD E
权利人:LILLY CO ELI
摘要:There is disclosed an improved method of synthesizing 5pyrimidinecarbinols by the addition of an alkyllithium to a mixture of 5-halopyrimidine and a ketone at a low temperature. The product compounds are useful as plant fungicides and as plant growth regulators.

专利号:US-2011021532-A1
优先权日:2008-04-22
标题 :Novel substituted heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：POWELL DAVID; LEBRUN MARIE-EVE; BHAT SATHESH; RAMTOHUL YEEMAN K
权利人:MERCK FROSST CANADA LTD
摘要:Substituted heteroaromatic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis. Formula (I).