CAS: 672-65-1; (1-Chloroethyl)Benzene

该化合物是一种卤化芳香化合物,配有分子式C8H9Cl.这种淡黄色液体无色的特征是其反应性苯乙烯氯,使它成为有机合成中有价值的中间体.其主要优点包括其在Friedel-Crafts藻类, Grignard反应以及作为制药和农用化学前体的用途.该化合物在受控条件下的稳定性和选择性回活动增强了其在精细化学制造中的可应用性.由于它的乳胶特性和潜在湿度敏感性,适当的处理是必不可少的.其定义明确的化学特性确保了专门合成应用的一贯性能.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号98-86-2 苯乙酮 | CAS号292638-84-7 phenylene-ethylene | CAS号98-85-1 苏合香醇 | CAS号57739-76-1 o-Bromo-α-methy... | CAS号100-41-4 乙苯 | CAS号4281-04-3 1,3,5-Cyclohept... | CAS号1517-69-7 (R)-(+)-1-苯基乙醇 | CAS号13466-30-3 1-Phenylethan-1... | CAS号111-71-7 正庚醛 | CAS号3910-35-8 1,3,3-三甲基-1-苯基茚满 | CAS号98-85-1 苏合香醇 | CAS号292638-84-7 phenylene-ethylene | CAS号32366-25-9 1-Phenylethyl azide | CAS号3299-05-6 1-乙氧基乙苯 | CAS号93-96-9 Benzene,1,1'-(o... | CAS号93-92-5 乙酸苏合香酯 | CAS号100-41-4 乙苯 | CAS号1524-12-5 1-phenylethyl 2... | CAS号492-37-5 2-苯基丙酸

合成工艺路线路线简述

    📜甲苄醇乙酸酯置于2-(甲硫基)噻吩,盐酸,N,N-二甲基丙烯基脲,溶剂黄146体系中,化学反应 6.0H,以98%的收率获得产物1-氯-1-苯乙烷
    参考文献:Metal-Free Regioselective Hydrochlorination Of Unactivated Alkenesviaa Combined Acid Catalytic System
    标题:Metal-Free Regioselective Hydrochlorination Of Unactivated Alkenesviaa Combined Acid Catalytic System
    摘要:一个结合了盐酸/hcl,Dmpu和乙酸的催化体系被用于对一系列未活化的烯烃进行氯化反应.
    DOI:10.1039/c7Gc03665E

    海关参考信息

    专利信息


    专利号:US-8461357-B2
    优先权日:2008-09-19
    标题 :Expeditious synthesis of gibberellin A5 and esters thereof
    发明人:FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS RICHARD P
    权利人:FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS R P; UTI LIMITED PARTNERSHIP
    摘要:An expeditious synthesis of gibberellin A 5 (GA 5 ) esters is presented, from which GA 5 may be prepared. The synthesis offers an inexpensive route of few steps to these compounds, starting from gibberellin A 3 (GA 3 ) esters in the presence of a metal hydride.

    专利号:US-5945548-A
    优先权日:1995-03-03
    标题:Process for the synthesis of α-substituted acrylic acids and their application
    发明人:DUHAMEL PIERRE; DUHAMEL LUCETTE; DANVY DENIS; MONTEIL THIERRY; LECOMTE JEANNE-MARIE; SCHWARTZ JEAN-CHARLES
    权利人:BIOPROJECT SOC CIV
    摘要:Process for the synthesis of α-substituted acrylic acids of general formula (I) and their application to the synthesis of N-(mercaptoacyl)aminoacid derivatives of formula (II). ##STR1##

    专利号:US-6800785-B1
    优先权日:2002-10-15
    标题:Process for the synthesis of estrogen receptor modulators
    发明人:MENG DONGFANG
    权利人:MERCK & CO INC
    摘要:The present invention relates to processes for the synthesis of intermediates useful for the synthesis of estrogen receptor modulators. The process includes new methods for annelating 5-, 6- and 7-membered cycloalkenones onto an indanone.

    专利号:US-6610802-B2
    优先权日:2001-05-29
    标题 :Process for synthesis of polymer compositions, polymer compositionS obtainable by the process, and use of the same
    发明人:ROOS SEBASTIAN; EISENBERG BORIS; HARPE CAROLIN
    权利人:ROHMAX ADDITIVES GMBH
    摘要:The present invention relates to a process for synthesis of polymer compositions with reduced catalyst content, wherein ethylenically unsaturated monomers containing less than 0.5 wt % of ethylenically unsaturated monomers with at least one carboxylic group, sulfonic acid group and/or at least one phosphonic acid group relative to the total weight of the ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts and, after the polymerization, the catalyst contained in the polymer is at least partly separated. For this purpose, the polymer composition is filtered, after the polymerization, in the presence of at least one filter aid which contains at least 0.5 wt %, relative to the total weight of the filter aid, of repeating units that contain at least one carboxylic acid group, sulfonic acid group and/or at least one phosphonic acid group.

    专利号:US-8450365-B2
    优先权日:2009-05-12
    标 题 :Efficient synthesis of galanthamine
    发明人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
    权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
    摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

    专利号:EP-0791575-A1
    优先权日:1996-02-16
    标题 :Method of synthesis of a quaternary ammonium salt
    发明人:NAKANO SHINJI
    权利人:NIPPON PAINT CO LTD
    摘要:The present invention provides an improved method of synthesis of a quaternary ammonium salt in which a tertiary amine is reacted with a benzyl halide optionally having on the benzene ring and/or at the α-site one ore more substituent groups inert to the reaction, which method is characterized in that the reaction is carried out in water or in a water-containing organic solvent.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Aldabbagh, F.; Gibbons, O., Science of Synthesis, (2010) 45, 731.
    摘要:Snaith, J. S., Science of Synthesis Knowledge Updates, (2011) 2, 167.
    摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 187.
    摘要:Gosmini, C.; Corpet, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 700.
    摘要:Schiltz, P.; Gosmini, C., Science of Synthesis: Special Topics, (2021) 1, 74.
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