CAS: 6106-21-4; Sodium Succinate Hexahydrate

丁二酸 在 Sodium Hydroxide体系中,用 甲醇,水作为反应溶剂,获得 Disodium Succinate Hexahydrate
参考文献:两种琥珀酸金属配合物[Lic2H2O2]2(S)和[Nac2H2O2.3H2O]2(S)的晶体结构,Hirshfeld表面和热化学性质的综合比较
标题:两种琥珀酸金属配合物[Lic2H2O2]2(S)和[Nac2H2O2.3H2O]2(S)的晶体结构,Hirshfeld表面和热化学性质的综合比较
摘要:在这项工作中,合成了两种琥珀酸的水性和非水性金属配合物,即琥珀酸锂(Ccdc:2284044)和六水合物琥珀酸钠(Ccdc:2296979).它们的晶体结构通过单晶x射线晶体学测定.琥珀酸锂以三角空间群结晶,六水琥珀酸钠以三斜空间群结晶.记录了两种配合物的赫什菲尔德表面和相应的二维指纹,表明琥珀酸锂之间的分子间相互作用的本质主要是配位键,而六水琥珀酸钠之间的分子间相互作用主要是分子间氢的形成.利用精密自动绝热量热仪测定了两种配合物在低温区间的实验热容,并通过拟合测量的实验热容,得到了热容随折叠转变温度变化的多项式方程最小二乘法,在此基础上计算了它们在低温区间以5 K为间隔的sulpine热容值以及它们相对于298.15 K的热力学函数值. Tg/Dsc 曲线还揭示了标题配合物的分子结构.
Doi:10.1016/J.Inoche.2023.111747

专利信息

专利号:US-12285423-B2
优先权日:2017-06-28
标题 :Composition for enhancing mitochondrial function
发明人：ANDREEVA LARISA; POMYTKIN IGOR ANATOLIEVICH; SKLADTCHIKOVA GALINA NONINA
权利人:MITOCHOLINE LTD
摘要:A method and composition for enhancing synthesis of adenosine triphosphate (ATP) in mitochondria of brain cells of a human includes providing the composition including a synergistic compound of choline cation and succinate anion (2-) in a molar ratio of choline:succinate of 2:1 in the form of dicholine succinate (DiSu) in a daily dosage that synergistically increases ATP levels in brain cells. The method and composition are formulated to affect frequency and/or severity of various conditions by regulating ATP levels in brain cells. The method and composition are formulated to reduce rate of decline in the brain under conditions of cerebral hypoxia, e.g., due to aging, injury, illness, and the similar conditions.

专利号:US-2025051274-A1
优先权日:2023-08-07
标 题 :Method for preparing 2-hydroxy-5-oxoproline
发明人：MARTINEZ RODOLFO; MARTINEZ NATHAN; BLASKOVIC ROBERT; GLASS DAVID REMBERT; UNKEFER CLIFFORD J
权利人:MILLENNIUM ENTPR INC
摘要:The compound 2-hydroxy-5-oxoproline salt can be used to produce an increase in carbon dioxide fixation, growth, dry weight, nutritional value (proteins and amino acids), nodulation and nitrogen fixation and photosynthetically derived chemical energy when applied to plants through their roots and/or through their foliar portions. The embodiments provide an improved chemical synthesis for this compound which is performed in a single step reaction using ozone with 2-pyrrolidone-5-carboxylic acid. The steps of dissolving Sodium 2-pyrrolidone-5-carboxylate in aqueous solution and reacting a molar excess of ozone with the aqueous solution of sodium 2-pyrrolidone-5-carboxylate at a temperature between 20° C. and 100° C. can be carried out such that sodium 2-hydroxy-5-oxoproline salt is formed.