CAS: 59229-09-3; 2,4,6-Trimethylpyridinium P-Toluenesulfonate

该化合物是一个有机化合物,其特征为丙烯酸和磺酸功能组; Pyridine是六人组成的芳香热循环,含有一个氮原子,有助于该化合物的基质和核分裂性; Pyridine环的2,4,4,6-三甲基,4-四甲基苯基硫酸(1:1),该物质体的分量增加,并能够影响该物质在各种溶剂中的再活性和溶解性.4-甲基苯基酸衍生的磺酸组在水中具有很大的极性和溶性,使该化合物在各种化学应用中有用,包括作为有机合成的试剂或催化剂.此外,该化合物可能表现出令人感兴趣的特性,如抗微生物活动或作为合成更复杂的分子的中间体.其稳定性和再活性可能受到亚体对亚基体对芳基体和化学的一个主题的影响.

结构式图片

相似化合物

93471-41-1 24057-28-1 91944-64-8

物理性质

MSDS等安全信息

欧盟法规

C&L通报

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-5597931-A
    优先权日:1992-03-30
    标 题:Total synthesis of taxol and analogues thereof
    发明人：DANISHEFSKY SAMUEL J; MASTERS JOHN; YOUNG WENDY; LINK J THOMAS; ISAACS RICHARD; SNYDER LAWRENCE B
    权利人:SLOAN KETTERING INST CANCER
    摘要:The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.

    专利号:US-5488116-A
    优先权日:1992-03-30
    标 题:Total synthesis of taxol and analogues thereof
    发明人：DANISHEFSKY SAMUEL J; BORNMANN WILLIAM G; QUENEAU YVES; MAGEE THOMAS V; KROL WALTER J; MASTERS JOHN J; JUNG DAVID K
    权利人:SLOAN KETTERING INST CANCER
    摘要:The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.

    专利号:US-5527924-A
    优先权日:1992-03-30
    标题 :Total synthesis of taxol
    发明人：DANISHEFSKY SAMUEL J; BORNMANN WILLIAM G; QUENEAU YVES; MAGEE THOMAS V; KROL WALTER J
    权利人:SLOAN KETTERING INST CANCER
    摘要:The present invention provides two basic routes for the total synthesis of taxol having the structure: The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogs to taxol. Both the intermediates and analogs to taxol may prove to be valuable anticancer agents.

    专利号:WO-9320036-A1
    优先权日:1992-03-30
    标 题:Total synthesis of taxol

    专利号:WO-9634862-A1
    优先权日:1995-05-05
    标 题 :Total synthesis of taxol and analogues thereof

    专利号:WO-9512567-A1
    优先权日:1993-11-02
    标题:Total synthesis of taxol and analogues thereof

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    主要参考文献

    [参考文献]: Wendy C Carcamo, Et Al. Induction Of Cytoplasmic Rods And Rings Structures By Inhibition Of The Ctp And Gtp Synthetic Pathway In Mammalian Cells. Plos One. 2011;6(12):E29690.

    合成参考文献


    摘要:Thomas, A. W., Science of Synthesis, (2007) 31, 374.
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