专利号:US-9126995-B2 优先权日:2011-11-08 标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound 发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU 权利人:NISSAN CHEMICAL IND LTD 摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.
专利号:US-2024043406-A1 优先权日:2020-12-18 标题 :Method for sequential one-pot synthesis of tkx-50 发明人:DELAGE ARTHUR; ECK GENEVIÈVE; ALAIME THIBAUD; LACEMON FRÉDÉRICK; KLAPOTKE THOMAS; STIERSTORFER JORG; BOLTER MARC 权利人:EURENCO FRANCE 摘要:The present invention relates to a sequential one-pot synthesis of TKX-50, suitable for larger-scale production, during which an acetyl halide is used during the cyclization of diazidoglyoxime so as to obtain 1,1′-diacetyl-5,5′-bistetrazole, which is then hydrolyzed to 5,5′-bistetrazole-1,1′-diolate, to which compound a hydroxylammonium salt is subsequently added.
专利号:EP-0444889-A1 优先权日:1990-02-26 标 题:Novel synthesis of carbapenem intermediates 发明人:RANO THOMAS A; GREENLEE MARK L; DININNO FRANK P 权利人:MERCK & CO INC 摘要:Carbapenems having the formula: are prepared by a novel reaction of a readily accessible carbapenem intermediate and an organostannane. The reaction, which is mediated by a palladium compound and, optionally, a phosphine ligand, proceeds at remarkably mild temperatures in reproducibly good yields.
专利号:US-2323861-A 优先权日:1942-11-21 标题:Synthesis of organic acids 发明人:ZELLNER CARL N 权利人:TIDE WATER ASSOCIATED OIL COMP
专利号:CN-105567746-B 优先权日:2015-12-31 标 题 :A kind of method of enzymatic synthesis of pyrethroid insecticide intermediate
专利号:EP-4263527-A1 优先权日:2020-12-18 标题 :Method for sequential one-pot synthesis of tkx-50