CAS: 538-32-9; Benzylurea

上下游产品

CAS号622-77-5 benzylcyanamide | CAS号64-17-5 乙醇 | CAS号90609-83-9 Carbamothioic a... | CAS号590-28-3 氰酸钾 | CAS号100-46-9 苄胺 | CAS号51-79-6 氨基甲酸乙酯 | CAS号57-13-6 尿素 | CAS号124-38-9 二氧化碳 | CAS号622-79-7 苄基叠氮 | CAS号556-89-8 硝基脲 | CAS号3173-56-6 异氰酸苄酯 | CAS号124-38-9 二氧化碳 | CAS号100-46-9 苄胺 | CAS号91360-95-1 1-苄基嘧啶-2,4,6(1h... | CAS号41862-11-7 6-氨基-1-苄基-1,2,3... | CAS号2142-01-0 N-苯甲基邻苯二甲酰亚胺 | CAS号112-30-1 正癸醇 | CAS号101780-25-0 1-benzyl-3-decylurea | CAS号72816-88-7 6-氨基-1-苄基-5-甲基氨基尿嘧啶 | CAS号65855-02-9 1-苄基-5-乙氧基海因

N-苄基硫脲置于双氧水体系中,用 乙醇 作为反应溶剂,化学反应生成 苄脲
参考文献:Walter,W.; Randau,G.,Justus Liebigs Annalen Der Chemie,1969,Vol. 722,P. 52-79
标题:Walter,W.; Randau,G.,Justus Liebigs Annalen Der Chemie,1969,Vol. 722,P. 52-79

专利信息

专利号:WO-2023086801-A1
优先权日:2021-11-09
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-2022267323-A1
优先权日:2019-07-23
标题 :Synthesis of bicyclic inhibitors of histone deacetylase
发明人：FULLER NATHAN OLIVER; HEWITT MICHAEL CHARLES; ASSELIN SYLVIE M; LUKE WAYNE DOUGLAS
权利人:ALKERMES INC
摘要:Provided herein are synthetic methods for the preparation of compounds having the Formula: (I) and (I′) and salts thereof.

专利号:WO-0061545-A1
优先权日:1999-04-14
标题 :Methods for solid phase combinatorial synthesis of integrin inhibitors
发明人：GOPALSAMY ARIAMALA; YANG HUI YU
权利人:AMERICAN HOME PROD
摘要:Compounds of the formula (I) are useful in the treatment of various disorders including, but not limited to, cancer (tumor metathesis, tumorgenesis/tumor growth), angiogenesis (as in cancer, diabetic retinopathy, rheumatoid arthritis), restenosis (following balloon angioplasty or stent implantation), inflammation (as in rheumatoid arthritis, psoriasis), bone diseases (osteopenia induced by bone metastases, immobilization and glucocortocoid treatment, periodontal disease, hyperparathyroidism and rheumatoid arthritis), and as antiviral agents. Novel method of making compounds of formula (I) are also provided.

专利号:WO-2024233848-A1
优先权日:2023-05-10
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

专利号:WO-9815532-A1
优先权日:1996-10-09
标 题:Solid phase synthesis of heterocyclic compounds
发明人：MARZINZIK ANDREAS; FELDER EDUARD
权利人:CIBA GEIGY AG; MARZINZIK ANDREAS; FELDER EDUARD
摘要:Here we report a study on a reaction sequence on solid phase, suitable for the generation of molecular diversity on small heterocycles. For each reaction, suitable conditions on solid phase were worked out and a variety of reactive agents (building blocks) was utilized in an effort to grasp the system's breadth of applicability. The inventive reaction sequence can be applied, for example, to exploit by the combinatorial approaches of the split and mix concept. The reaction sequence comprises the following steps: a) a solid carrier having reactive surface groups is loaded directly or via a spacer group with a compound bearing an aldehyde or a methylketon function, b) said function is modified using the Witting reaction or the aldol condensation, c) the heterocyclic ring is closed using a compound comprising two nucleophiles, wherein at least one of the said nucleophiles is NH2.

专利号:US-6235910-B1
优先权日:1998-09-22
标题:Process for the preparation of imidazolidine-2, 4-diones
发明人：BELLER MATTHIAS; ECKERT MARKUS; MORADI WAHED
权利人:DEGUSSA
摘要:A process for the preparation of compounds of the general formula (I)by reacting an aldehyde compound of the general formula (II)with a urea compound of the general formula (III)in the presence of carbon monoxide and a catalytically active metal compound. Compounds of the general formula (I) are important intermediates for the synthesis of alpha-amino acids.