CAS: 458-46-8; 3-Fluorocinnamic Acid

上下游产品

malonic acid 3-Fluorobenzaldehyde 3-(3-fluorophenyl)acrylic acid methyl ester 3-fluorostyrene ethyl 3-(3-fluorophenyl)acrylate 3-fluoro-cinnamoyl chloride 3-(3-fluorophenyl)acrylic acid methyl ester

3-(3-氟苯基)丙烯酸甲酯置于lithium Hydroxide Monohydrate体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 2.0H,以75%的收率获得产物3-氟肉桂酸
参考文献:2-苯基环丙基甲基胺衍生物及其制备方法和用途
标题:2-苯基环丙基甲基胺衍生物及其制备方法和用途
摘要:本发明公开了一种2‑苯基环丙基甲基胺衍生物及其制备方法和用途.本发明的2‑苯基环丙基甲基胺衍生物具有如下式i所示的结构,其具有对多巴胺受体和/或5‑羟色胺受体的亲和活性,可以用于治疗精神类疾病.

专利信息

专利号:US-5981239-A
优先权日:1997-09-24
标 题 :Synthesis of optically active phenylalanine analogs using Rhodotorula graminis
发明人：LIU WEIGUO
权利人:GREAT LAKES CHEMICAL CORP
摘要:A biocatalytic process to produce optically active phenylalanine analogs from arylacrylic acids is disclosed in which Rhodotorula graminis yeast containing phenylalanine ammonia-lyase introduces a molecule of ammonia stereoselectively onto the double bond of a 3-substituted acrylic acid. The substituent at the 3-position of the 3-substituted acrylic acid includes, for example, aromatic rings such as substituted phenyl groups, five member aromatic heterocyclics, and six member aromatic heterocyclics.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-3975429-A
优先权日:1973-11-05
标题:Cyclopropanemethyl esters of cinnamic acid and derivatives thereof
发明人：HENRICK CLIVE A; STAAL GERARDUS B
权利人:ZOECON CORP
摘要:Organic esters and thioesters characterized by the presence of a cyclopropane moiety, synthesis thereof, and compositions thereof for the control of mites and ticks.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.