CAS: 41059-02-3; 9-Bromononanoic Acid

该化合物是含有分子式C9H17BRO2的溴化箱式酸,该化合物是有机合成的多用途中间体,特别是在准备-功能化脂肪酸及其衍生物时.其末期溴原子能够产生高效的烷酸或核生殖替代反应,使其对建造具有定制功能的长链分子很有价值.该酸组允许进一步修改,如洗涤或恐吓.9-Broomonanoic酸通常用于制药研究,聚合化学和表面活性剂开发,其明确界定的结构和再活动确保多步骤合成路线的一贯性能.由于可能具有刺激性,因此建议适当处理.

英文名称9-Bromononanoic Acid
中文名称9-溴壬酸
IUPAC名称9-bromononanoic acid
其它别名Nonanoic Acid, 9-Bromo-; 9-Bromo-N-Nonanoic Acid; 9-Bromononanoicacid; 9-Bromononanoic Acid; 9-Bromo-Nonanoic Acid; 9-Bromo Nonan
CAS编号41059-02-3
MFCD编号:MFCD00046564
EINECS号:676-389-1
分子式:C9H17BrO2
分子量:237.14
产品CID: 1424962
产品分类有机原料 → 羧酸类化合物及衍生物

相似结构搜索
InChIKey: XEGRKZRPTBNSMN-UHFFFAOYSA-N
InChI=1S/C9H17BrO2/c10-8-6-4-2-1-3-5-7-9(11)12/h1-8H2,(H,11,12)…
计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数8.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别皮肤腐蚀类别1B
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
金属腐蚀物类别1
皮肤腐蚀类别1C
严重眼损伤类别1
警示词Warning(警告)
危险描述H314 |造成严重皮肤灼伤和眼损伤.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H290 |可能对金属造成腐蚀.
H318 |造成严重眼损伤.
防范说明P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P405-P406-P501
危险等级IRRITANT
UN编号3261
危险品标志Xi
包装等级III
安全声明36/37/39
危险类别码34

欧盟法规

ECHA物质C&L通报

上下游产品

9-羟基壬酸 9-Hydroxynonanoic Acid 3788-56-5
9-溴壬酸乙酯 Ethyl 9-Bromononanoate 28598-81-4
9-溴-1-壬醇 9-Bromononan-1-Ol 55362-80-6
壬二酸二甲酯 Dimethyl Azelate 1732-10-1

合成工艺路线路线简述

合成目标产物 9-Bromononanoic Acid 主要起始原料 9-Bromo-1-Nonanol
(文献来源)合成步骤主要原料 9-Bromo-1-Nonanol

9-溴-1-壬醇置于jones Reagent体系中,用丙酮作为反应溶剂,以21.4%的收率获得产物9-溴壬酸
参考文献:Peptidomimetic Inhibitors Ofn-Myristoyltransferase From Human Malaria And Leishmaniasis Parasites
标题:Peptidomimetic Inhibitors Ofn-Myristoyltransferase From Human Malaria And Leishmaniasis Parasites
摘要:肽类模拟抑制剂已经被设计出来,针对疟疾和利什曼病寄生虫中的n-肟基转移酶,具有纳摩尔级的效力,并展示了第一个直接的结构证据,证明了一个三元复合物nmt/coa/myristoyl肽产物的存在.
DOI:10.1039/c4Ob01669F

海关参考信息

2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛
2912120000-乙醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-4645858-A
优先权日:1982-03-22
标题 :Pentanedioic acid derivatives
发明人：LOWRIE HARMAN S; BARAN JOHN S
权利人:SEARLE & CO
摘要:Compounds of formula I are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit Î²-hydroxy-Î²-methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.

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优先权日:2020-12-04
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发明人：ALI MIR; BOESCH AUSTIN WAYNE; DRUMMOND DARYL CLARK; KUHLMAN WILLIAM; NIELSEN ULRIK
权利人:TIDAL THERAPEUTICS INC
摘要:Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles.

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优先权日:2021-07-07
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专利号:TW-202241458-A
优先权日:2020-12-04
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优先权日:2020-12-04
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