CAS: 25474-85-5; 4-Methoxybenzyloxycarbonyl Azide

上下游产品

4-methoxybenzyl hydrazinecarboxylate 4-methoxybenzyl phenyl carbonate (S)-2-(4-Methoxy-benzyloxycarbonylamino)-propionic acid carbonyl>-L-serineN-(p-methoxybenzyl)oxycarbonyl-L-serine Z(OMe)-Leu-OH Z(OMe)-Met-OH

📜4-甲氧基苄氧基酰肼置于溶剂黄146,Sodium Nitrite体系中,化学反应生成4-甲氧基苄氧基羰酰叠氮物
参考文献:Weygand,F.; Hunger,K.,Chemische Berichte,1962,Vol. 95,P. 1-6
标题:Weygand,F.; Hunger,K.,Chemische Berichte,1962,Vol. 95,P. 1-6

专利信息

专利号:US-3592836-A
优先权日:1966-12-23
标 题:Aryloxycarbonyl fluorides and amino acids and their production
发明人：UGI IVAR; KLAUKE ERICH; SCHNABEL EUGEN; HOFFMANN PETER
权利人:BAYER AG
摘要:ARYLOXYCARBONYL FLUORIDES SUCH AS FURFURYLOXYCARBONYL-, P-METHOXYBENZYLOXYCARBONYL- AND TRIMETHOXYBENZYLOXYCARBONYL-FLUORIDES ARE PROVIDED WHICH ARE USEFUL AS INTERMEDIATES FOR AMINO ACID DERIVATIVES AND ARE OBTAINED FROM CARBONYL-FLUORIDE CHLORIDE BY REACTION WITH THE APPROPRIATE ALCOHOL. THE AMINO ACID DERIVATIVES OF SUCH CARBONYL-FLUORIDES ARE BUILT UP THROUGH ACYLATION OF AMINO ACIDS THEREWITH. THESE AMINO ACID DERIVATIVES ARE USEFUL AS INTERMEDIATES FOR THE SYNTHESIS OF POLYPEPTIDES. THE REACTION OF CARBONYLCHLORIDE-FLUORIDE IS ADVANTAGEOUSLY CARRIED OUT AT TEMPERATURES OF 0 TO 70*C. IN AN INERT SOLVENT AND IN THE PRESENCE OF AN ACID-BINDING AGENT. THE AMINO ACID DERIVATIVES ARE FORMED AT TEMPERATURES BETWEEN +20 AND -20*C. ALSO IN THE PRESENCE OF AN ACID-BINDING AGENT. IMINO ACIDS CAN BE USED IN PLACE OF AMINO ACIDS. THE AMINO- OR IMINO-ACID DERIVATIVES OR ESTERS ARE ADVANTAGEOUSLY PREPARED AT CONSTANT. CONTROLLED PH VALUES, PREFERABLY BY THE USE OF AUTOMATIC PH CONTROL EQUIPMENT.

专利号:ES-2333781-T3
优先权日:2001-09-07
标 题 :SYNTHESIS PROCEDURES OF INSULIN-OLIGOMERO POLYPEPTIDE CONJUGATES AND PROINSULIN-OLIGOMERO POLYPEPTIDE CONJUGATES, AND SYNTHESIS PROCEDURES OF THE SAME.