CAS: 19418-11-2; Tetrahydrothiophene-2-Carboxylic Acid

相似化合物

17570-08-0 63358-63-4 38518-31-9

上下游产品

2-thiophenylcarboxylic acid tetrahydrothiophene-2-carbonitrile 5-chloro-2-mercapto-valeric acid methyl ester (3-Chloropropylthio)acetonitrile tetrahydrothiophene-2-carbonyl chloride Cyclohex-2-enol Tetrahydrothiophene-2-carboxanilide porphyrin5,10,15,20-tetrakisporphyrin

📜1-(2-噻吩基)-1-丙酮置于sodium Amalgam,Alkaline Permanganate体系中,化学反应生成四氢-2-噻吩羧酸
参考文献:Ernst,Chemische Berichte,1887,Vol. 20,P. 518
标题:Ernst,Chemische Berichte,1887,Vol. 20,P. 518

专利信息

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-4381301-A
优先权日:1980-05-07
标题 :Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments
发明人：RAINER GEORG
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:Substituted thienobenzodiazepinones of the general formula I (I) [wherein R1 denotes a hydrogen atom (-H) or an alkyl radical with 1 to 4 carbon atoms; R2 represents a halogen atom (halo) or has one of the meanings of R1; R3 denotes a halogen atom (halo) or the group -N(R4)R5; R4 denotes an alkyl radical with 1 to 4 carbon atoms or an alkenyl radical with 3 to 5 carbon atoms; R5 has one of the meanings of R4 or represents the group -(CH2)m-N(R6)R7; or R4 and R5, together with the nitrogen atom to which both are bonded, denote a morpholino group, a pyrrolidino group, a piperidino group, a hexahydroazepin-1-yl group, a piperazin-1-yl group (which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group), a 2,4-dimethylpiperazin-1-yl group, or a hexahydro-1H-1,4-diazepin-1-yl group (which is substituted in the 4-position by a methyl or ethyl group); R6 denotes an alkyl group with 1 to 4 carbon atoms; R7 denotes an alkyl group with 1 to 4 carbon atoms; A denotes a straight-chain or branched alkylene group with 1 to 5 carbon atoms; and m denotes 2 or 3] and their acid-addition salts are new compounds. They either have a protective action on the stomach and intestine and are suitable for treating illnesses based on disorders of the stomach or intestine, or they are intermediates for preparing products having protective action. Processes for the preparation of the new pharmacologically-active compounds and of the intermediate products are presented.

专利号:US-2024002331-A1
优先权日:2022-06-08
标 题 :Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
发明人：ALI MIR; BOESCH AUSTIN WAYNE; DRUMMOND DARYL CLARK; KUHLMAN WILLIAM; NIELSEN ULRIK
权利人:TIDAL THERAPEUTICS INC
摘要:Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles.

专利号:CN-1151146-C
优先权日:1994-04-23
标题 :Process for diastereoselective synthesis of nucleoside analogues

专利号:WO-2023240156-A9
优先权日:2022-06-08
标 题 :Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof

专利号:IL-303373-A
优先权日:2020-12-04
标题 :Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof