CAS: 16649-50-6; N-(Tert-Butyl)Hydroxylamine

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N-(叔丁基)羟胺乙酸酯置于碳酸氢钠体系中,化学反应生成N-叔丁基羟胺
参考文献:Novel Compounds As Cannabinoid Receptor Ligands
标题:Novel Compounds As Cannabinoid Receptor Ligands
摘要:本文揭示了公式(i)中的大麻素受体配体,其中a1,A5,Rx,X4和z如规范中定义.还公开了包含这些化合物的组合物,以及使用这些化合物和组合物治疗疾病和疾病的方法.

专利信息

专利号:US-2023212216-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins
发明人：MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
权利人:GENIE BIOTECH UK LTD
摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

专利号:US-11904268-B2
优先权日:2017-07-28
标题 :Preparation of new aldehyde and/or ketone traps and filters
发明人：TRAN-THI THU-HOA; BORTA ANA; GINEYS MICKAEL; SOM MARIE-PIERRE; HAMMEL FRÉDÉRIC
权利人:COMMISSARIAT ENERGIE ATOMIQUE; CENTRE NATIONAL DE LA RECH SCIENTIFIQUE—CNRS—
摘要:A method for preparing a nanoporous silica sol-gel matrix containing at least one amine reactant selected from hydroxylamine, methylhydroxylamine, tertbutylhydroxylamine, methoxyamine, tetraethylenepentamine, dicarboxylic acid dihydrazides, particularly adipic acid dihydrazide, and the salts thereof, said method including the following steps: a) synthesising a gel from tetramethoxysilane or from a mixture of tetramethoxysilane and another organosilicon precursor selected from among phenyltrimethoxysilane, phenyltriethoxysilane, a fluoroalkyltrimethoxysilane, a fluoroalkyltriethoxysilane, a chloroalkylmethoxysilane, a chloroalkylethoxysilane, an alkyltrimethoxysilane, an alkyltriethoxysilane, an aminopropyltriethoxysilane and the mixtures thereof, the synthesis being performed in an aqueous medium at a temperature ranging from 10 to 70° C. in the presence of at least one amine reactant selected from among hydroxylamine, methylhydroxylamine, tertbutylhydroxylamine, methoxyamine, dicarboxylic acid dihydrazides, particularly adipic acid dihydrazide, and the salts thereof; b) drying the gel obtained during step a) so as to obtain a sol-gel matrix containing at least one amine reactant.

专利号:AU-2020409711-A1
优先权日:2019-12-20
标题 :Synthesis of lactone derivatives and their use in the modification of proteins

专利号:US-6512143-B1
优先权日:1998-07-10
标 题:Salts of N-tert-butylhydroxylamine
发明人：BLIXT JOERGEN
权利人:ASTRAZENECA AB
摘要:Novel salts of N-tert-butylhydroxylamine with lower carboxylic acids are disclosed, together with processes for their preparation. The salts possess advantageous properties that render them useful in synthesis.

专利号:EP-4076533-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins

专利号:CA-3164962-A1
优先权日:2019-12-20
标题 :Synthesis of lactone derivatives and their use in the modification of proteins