CAS: 155-58-8; (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-3-Hydroxy-4-Methoxystyryl)Phenoxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
该化合物是一种天然的化合物,被归类为氟氯素胶质,主要来源于rhubarb工厂的根,特别是Rheum rhaponticum.该化合物的特点是其苯球结构,它有助于其潜在的抗氧化特性.Rhaponticin以其各种生物活动而著称,包括防炎,抗微生物和潜在的抗癌效应,因此它具有药物学研究的兴趣.该化合物通常以晶体形式出现,在极地溶剂中溶解,便于其从植物材料中提取.其化学结构包括糖味,它增加了其溶性性和生物利用率.它因其在传统医学中的作用及其在饮食补充中的潜在用途而进行了研究.然而,有必要开展进一步研究,以充分阐明其行动和治疗潜力的机制.
- 英文名称(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-3-Hydroxy-4-Methoxystyryl)Phenoxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
- 中文名称大黄苷
- IUPAC名称(2S,3R,4S,5S,6R)-2-(3-hydroxy-5-((E)-3-hydroxy-4-methoxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
- 其它别名Rhapontin(6CI,7CI,8CI); b-D-Glucopyranoside,3-hydroxy-5-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenyl, (E)-; 3,3',5-Trihydroxy-4'-methoxystilbene 3-b-D-glucopyranoside; 4'-Methoxy-3,3',5-stilbenetriol 3-b-D-glucopyranoside; Ponticin; Rhaponticin; Rhaponticoside; Rhapontinum
- CAS编号155-58-8
- MFCD编号:MFCD00010117
- EINECS号:205-845-0
- FDA UNII编号:K691M2Z08V
- 分子式:C21H24O9
- 分子量:420.41
- 产品CID: 771806
- 产品分类首页→产品中心
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: GKAJCVFOJGXVIA-DXKBKAGUSA-N
- GKAJCVFOJGXVIA-DXKBKAGUSA-N…
- 计算化学: 氢键受体数9.0氢键供体数6.0可旋转键数6.0
物理性质
MSDS等安全信息
上下游产品
CAS号621-58-9 3-hydroxy-4-met... | CAS号621-59-0 异香兰素； 3-羟基-4-甲氧... | CAS号25245-27-6 3,5-二甲氧基碘苯 | CAS号10272-07-8 3,5-二甲氧基苯胺 | CAS号604-68-2 α-D-葡萄糖五乙酸酯 | CAS号500-65-2 丹叶大黄素合成工艺路线路线简述
- 500-65-2 + 572-09-8 = 155-58-8 + 94356-22-6
反应条件:1.1 Catalysts: Potassium Hydroxide Solvents: Ethanol; 24 H,Rt
标题:Method For Producing Glycosylated Stilbenoid Compounds
参考文献:World Intellectual Property Organization
3,5-二甲氧基碘苯置于三乙醇胺,Palladium Diacetate,三溴化硼,Silver Carbonate体系中,用 二氯甲烷,乙腈 用作溶剂,化学反应 24.0H,反应生成勒胖停
参考文献:A Short Synthesis Of Rhaponticin And Its 3"-Fluoroanalog Via A Wittig/heck-Mizoroki Route
标题:A Short Synthesis Of Rhaponticin And Its 3"-Fluoroanalog Via A Wittig/heck-Mizoroki Route
摘要:胡薄荷次苷及其3"-氟类似物已从易得的起始原料中制备得到.这些合成中的关键步骤是使用碳酸银介导的糖苷化反应,用于选择性地形成β-糖苷键.在三乙醇胺中通过钯醋酸盐催化的heck-Mizoroki反应,在同时去保护糖类的情况下,建立了芪类化合物的(E)构型.
Doi:10.1515/znb-2011-0314
海关参考信息
- 2901210000-乙烯
2902300000-甲苯
2902500000-苯乙烯
2905122000-异丙醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6479466-B1
优先权日:1999-08-13
标题:Compositions for treating viral infections, and methods therefor
发明人：REDFIELD ROBERT R; DAVIS JR CHARLES E; HEREDIA ALONSO
权利人:UNIV MARYLAND; UNIV MARYLAND BIOTECH INST
摘要:Methods and combinations of an agent that promotes DNA synthesis in a virally-targeted cell and a nucleoside analogue having antiviral activity are provided for treating a viral infection in a subject in need thereof. Such compositions are particularly effective where the subject has resistance to a nucleoside analogue, where the subject has resting cellular reservoirs of such a virus, or to induce a post-treatment period of replication incompetence of such a virus.
专利号:CN-115612114-A
优先权日:2021-07-14
标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
网址: http://www.cdmust.com
电话: 028-87384368👤
销售电话:028-87384368
邮箱：cdmust@163.com
电话: 028-87384368👤
📞成都曼思特生物科技有限公司 ⚠️参考联系方式
销售电话:028-87384368
邮箱：cdmust@163.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领，请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实，百琢研不参与任何交易。企业认领注册入口→
⚠️ 未注册 · 未认证企业
备注: 📌 数据来源说明：本展台内容基于各搜索引擎等公开数据整理，仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议， 请通过页面底部联系方式告知我们，我们会尽快处理。第 1 / 1 页
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Wei W, Wang L, Zhou K, Xie H, Zhang M, Zhang C. Rhapontin ameliorates colonic epithelial dysfunction in experimental colitis through SIRT1 signaling. Int Immunopharmacol. 2017 Jan;42:185-194. doi: 10.1016/j.intimp.2016.11.024. Epub 2016 Dec 5. 80(13):1067-71. doi: 10.1055/s-0034-1382999. Epub 2014 Aug 15.
47:38-46. doi: 10.1016/j.intimp.2017.03.020. Epub 2017 Mar 30. 76(12):2307-9. doi: 10.1271/bbb.120229. Epub 2012 Dec 7.
11:1413214. doi: 10.3389/fmolb.2024.1413214.
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
参考文献:10.1021/acs.jnatprod.7b00384
摘要:Eräsalo H, Hämäläinen M, Leppänen T, Mäki-Opas I, Laavola M, Haavikko R, Yli-Kauhaluoma J, Moilanen E. Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner. J Nat Prod. 2018 May 25;81(5):1131–42. doi: 10.1021/acs.jnatprod.7b00384.
参考文献:10.4014/jmb.0907.07022
摘要:Kim J, Kim N, Lim Y. Evaluation of the Antibacterial Activity of Rhapontigenin Produced from Rhapontin by Biotransformation against Propionibacterium acnes. Journal of Microbiology and Biotechnology. 2010 Jan 28;20(1):82–7. doi: 10.4014/jmb.0907.07022.
📝 需求与反馈
尽可能描述清楚需求与问题信息
