CAS: 10130-74-2; 3-Methoxybenzene-1-Sulfonyl Chloride

该化合物是一种有机化合物,其特点是附于一个甲基氧代苯苯环的全氟辛烷磺酸功能组,其分子结构中含有一个苯环,其甲氧基组(-OCH)相对于全氟氯化物组(-SOCl)的元位置.该化合物一般是色素不及色的黄色液体,以其反应性为名,特别是核糖代用品反应,可用作灭菌剂,在二氯乙烷和乙醚等有机溶剂中溶解,但一般在水中是溶解.3-甲基氧苯并硫化物氯化物在有机合成中使用,特别是用于制作磺酰胺和其他磺酰氟衍生物.鉴于其反应性质,应谨慎处理,因为它可引起皮肤,眼睛和呼吸系统刺激.在使用个人防护设备时,包括使用这种化合物时,应使用适当的安全措施.

结构式图片

相似化合物

98-68-0 914261-11-3 220227-84-9

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号536-90-3 间氨基苯甲醚 | CAS号19183-05-2 3-methoxybenzen... | CAS号15570-12-4 3-甲氧基苯硫酚 | CAS号59014-89-0 1-methoxy-3-[(3... | CAS号17113-78-9 1-Methoxy-3-(tr... | CAS号122439-11-6 三丁基(3-甲氧基苯基)锡 | CAS号2113-56-6 3-甲氧基联苯 | CAS号58734-57-9 3-茴香醚磺酰胺 | CAS号15570-12-4 3-甲氧基苯硫酚

合成工艺路线路线简述

    (3-甲氧基苯基)(三甲基)锡烷置于磺酰氯体系中,化学反应 4.0H,反应生成3-甲氧基苯磺酰氯
    参考文献:Lube,Andreas; Neumann,Wilhelm P.; Niestroj,Michael,Chemische Berichte,1995,Vol. 128,# 12,P. 1195-1198
    标题:Lube,Andreas; Neumann,Wilhelm P.; Niestroj,Michael,Chemische Berichte,1995,Vol. 128,# 12,P. 1195-1198

    专利信息


    专利号:US-9574189-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries
    发明人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
    权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
    摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

    专利号:US-2023192718-A1
    优先权日:2018-03-30
    标 题 :Bicyclic enone carboxylates as modulators of transporters and uses thereof
    发明人:SANDANAYAKA VINCENT
    权利人:NIROGY THERAPEUTICS INC
    摘要:The invention generally relates to the field of monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate enone compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.

    专利号:US-11702652-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2009264300-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:EP-1836163-B1
    优先权日:2004-12-23
    标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
    发明人:BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
    权利人:NOVARTIS AG
    摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

    专利号:US-2020216836-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Hanumegowda Raju, Et Al. Synthesis, Characterization And In-Vitro Antiproliferative Effects Of Novel 5-Amino Pyrazole Derivatives Against Breast Cancer Cell Lines. Recent Pat Anticancer Drug Discov. 2011 May;6(2):186-95.

    合成参考文献


    摘要:Shcherbakova, I., Science of Synthesis, (2007) 31, 785.
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