CAS: 866782-59-4; 8-Fluoro-3-Iodoquinoline

相似化合物

394-68-3 79476-07-6 1367870-77-6

上下游产品

CAS号394-68-3 8-氟喹啉

8-氟喹啉置于n-碘代丁二酰亚胺体系中,用 溶剂黄146 作为反应溶剂,化学反应 20.5H,以70%的收率获得产物8-氟-3-碘喹啉
参考文献: 3-((Hetero)Arylsulfonyl)-8-` (Aminoalkyl)Oxy!Quinolines As 5-Ht6 Receptor Antagonists For The Treatment Of Cns Disorders[fr] 3-((Hetero)Arylsulfonyl)-8-{(Aminoalkyl)Oxy}Quinolines Servant D'Antagonistes Au Recepteur 5-Ht6 Pour Le Traitement De Troubles Cns
标题: 3-((Hetero)Arylsulfonyl)-8-` (Aminoalkyl)Oxy!Quinolines As 5-Ht6 Receptor Antagonists For The Treatment Of Cns Disorders[fr] 3-((Hetero)Arylsulfonyl)-8-{(Aminoalkyl)Oxy}Quinolines Servant D'Antagonistes Au Recepteur 5-Ht6 Pour Le Traitement De Troubles Cns
摘要:本发明涉及新型喹啉衍生物,如式(I)化合物,以及在治疗中枢神经系统和其他疾病中使用这些化合物或其药物组合物.

专利信息

专利号:US-2008255359-A1
优先权日:2005-09-28
标题:Novel Chemical Process For the Synthesis of Quinoline Compounds
发明人：WADE CHARLES EDWARD
权利人:WADE CHARLES EDWARD
摘要:Disclosed is a novel, simplified and economic process for making 3-phenylsulphonyl quinolines with an amine group at position 8 of the quinoline ring system, including 3-phenylsulfonyl-8-piperazin-1-yl-quinoline in particular, in the absence of a palladium catalyst. Also disclosed is the crystallization of polymorphic forms of 3-phenylsulfonyl-8-piperazin-1-yl-quinoline.

专利号:EP-1928832-A1
优先权日:2005-09-28
标 题 :Novel chemical process for the synthesis of quinoline compounds

专利号:WO-2007039238-A1
优先权日:2005-09-28
标题 :Novel chemical process for the synthesis of quinoline compounds