CAS: 74472-50-7; 2,3,3',4,4',5',6-Heptachlorobiphenyl

该化合物是多氯代联苯(PCB)家族的成员,该家族由多氯代联苯分子组成,该化合物的特点是联苯结构附带七氯原子,有助于其稳定性和在环境中的持久性;七氯联苯的特点是其具有疏水性,挥发性低和抗降解性,这可能导致生物生物体的生物累积;它通常存在于工业应用中,尽管由于毒理学影响,包括潜在的致癌性和内分泌干扰,它已被限制或禁止使用;该化合物具有亲脂性,它往往会积累在脂肪组织中,对野生动物和人类健康造成危险;环境监测往往在土壤,沉积物和生物群中发现此类化合物,引起人们对其长期生态影响的关切;适当处理和处置对于减轻与接触这种物质和类似物质有关的风险至关重要.

英文名称2,3,3',4,4',5',6-Heptachlorobiphenyl
中文名称2,3,3',4,4',5',6-七氯联苯
IUPAC名称1,2,3,5-tetrachloro-4-(3,4,5-trichlorophenyl)benzene
其它别名2,3,3',4,4',5',6-HEPTACHLOROBIPHENYL; 1,2,3,5-tetrachloro-4-(3,4,5-trichlorophenyl)benzene; 2,3,3',4,4',5',6-HEPTACB CERTIFIED STANDARD
CAS编号74472-50-7
MFCD编号:MFCD00674483
FDA UNII编号:895SJ405CI
分子式:C12H3Cl7分子量:395.32
产品CID: 1734798
产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃

相似结构搜索
InChIKey: TVFXBXWAXIMLAQ-UHFFFAOYSA-N
1S/C12H3Cl7/c13-5-3-8(16)11(18)12(19)9(5)4-1-6(14)10(17)7(15)2-4/h1-3H
计算化学: 氢键受体数*氢键供体数*可旋转键数1.0

MSDS等安全信息

危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

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合成工艺路线路线简述

📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于air体系中,化学反应生成 2,3,3',4,4',5',6-七氯联苯
参考文献:英国国内煤炭和木材燃烧产生的pcdd / Fs,Pcbs,Pcns,Pahs和pm10的排放因子和重要性
标题:英国国内煤炭和木材燃烧产生的pcdd / Fs,Pcbs,Pcns,Pahs和pm10的排放因子和重要性
摘要:本文介绍了当煤和木材经过受控燃烧实验时针对一系列持久性有机污染物(pops)得出的排放因子(efs),旨在模拟空间供暖的家庭燃烧.排放了各种各样的持久性有机污染物,煤炭的排放量高于木材的排放量.对于颗粒物,Pm10(大约10 G / Kg燃料)和多环芳烃(对于sigmapahs大约100 Mg / Kg燃料)获得了最高的ef.对于氯化物,多氯联苯(pcb)的ef最高,而多氯萘(pcn),二苯并-对-二恶英(pcdd)和二苯并呋喃(pcdf)的丰度较低.对于sigmapcb,Ef大约为1000 Ng / Kg燃料,对于sigmapcns大约为100S Ng / Kg燃料,对于sigmapcdd / Fs大约为100 Ng / Kg燃料.该研究证实,一氯化至三氯化二苯并呋喃cl1,2,3Dfs是低温燃烧过程(如煤炭和木材的国内燃烧)的有力指标.结论是,在固体燃料燃烧期间通常形成许多pcb和pc
DOI:10.1021/es048745I