CAS: 6059-47-8; Codeine Hydrate

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    专利号:US-8450365-B2
    优先权日:2009-05-12
    标 题 :Efficient synthesis of galanthamine
    发明人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
    权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
    摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

    专利号:US-2015133664-A1
    优先权日:2012-06-07
    标 题:Chemical transformations of (-)-codeine to afford derivatives of codeine and morphine thereof
    发明人:MAGNUS PHILIP; GHAVIMI-ALAGHA BAHMAN
    权利人:UNIV TEXAS
    摘要:The present invention relates to methods for the synthesis of morphine, codeine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency, steroselectivity, and overall yield of said codeine and morphine related derivatives and intermediates thereof. The present invention relates to new codeine and morphine related derivative compositions.

    专利号:US-8546454-B2
    优先权日:2011-07-26
    标题 :Process and method for the producton of dimethylether (DME)
    发明人:RANDHAVA SARABJIT S; KAO RICHARD L; HARVEY TODD L
    权利人:RANDHAVA SARABJIT S; KAO RICHARD L; HARVEY TODD L; UNITEL TECHNOLOGIES INC
    摘要:Disclosed herein is a process for the production of fuel grade DME from carbonaceous fuels, including a pressurized multi-stage progressively expanding fluidized bed gasifier and an oxyblown autothermal reformer to produce a synthesis gas (syngas) with desirable hydrogen to carbon monoxide molar ratio, which then undergoes gas-phase DME one-step direct synthesis in a fluid pluralized bed reactor over an attrition resistant bifunctional catalyst. The crude DME thus obtained is purified in a two column distillation unit to produce a fuel grade DME having a purity greater than 99.98 mole %.

    专利号:US-9994558-B2
    优先权日:2013-09-20
    标题 :Multicyclic compounds and methods of using same
    发明人:BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
    权利人:KARYOPHARM THERAPEUTICS INC
    摘要:The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., PAK-mediated, for example, PAK4-mediated, diseases and disorders).

    专利号:US-2003167692-A1
    优先权日:2000-05-05
    标题 :Method for increasing the efficiency of a gasification process for halogenated materials
    发明人:JEWELL DENNIS W; HENLEY JOHN P; GALLOWAY CONNIE M
    摘要:Methods for improving a gasification process for halogenated materials and in particular for producing useful end products such as anhydrous or highly concentrated hydrogen halides and/or synthesis gas, the methods including recycling water/hydrogen halide vapors and/or carbon dioxide to a gasification reactor.

    专利号:US-12084407-B2
    优先权日:2019-11-26
    标 题 :Cannabigerol derivatives and use thereof as cannabinoid receptor modulators
    发明人:AHMAR SIAWASH; GNANASEKARAN KRISHNA KUMAR; OMEARA JEFFREY ALAN
    权利人:CANOPY GROWTH CORP
    摘要:The synthesis of a range of pentylbezene-1,3-diol compounds of formula I is disclosed. These compounds bind to cannabinoid 1 and 2 receptors (CB1 and CB2), and are thus presumed to be useful in modulating the activity of such receptors. Accordingly, the use of such synthetic cannabinoids in the treatment of various disorders mediated by CB1 and CB2 is contemplated.

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    主要参考文献

    参考标题: Synthesis Of Morphine And Related Derivatives Synthèse De La Morphine Et De Dérivés Associés
    摘要:The Present Invention Relates To Methods For The Synthesis Of Galanthamine, Morphine, Intermediates, Salts And Derivatives Thereof, Wherein The Starting Compound Is Biphenyl.

    合成参考文献


    参考文献:10.1021/mp500334z
    摘要:Braun DE, Gelbrich T, Kahlenberg V, Griesser UJ. Insights into hydrate formation and stability of morphinanes from a combination of experimental and computational approaches. Mol Pharm. 2014 Sep 02;11(9):3145–63.
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