CAS: 548769-96-6; (4-(N-Benzylsulfamoyl)Phenyl)Boronic Acid

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benzylamine methyl-phenyl-carbamic acid 4'-benzylsulfamoyl-biphenyl-4-yl ester [4-(4-benzylsulfamoyl-phenyl)-6-chloro-3-methyl-naphthalen-2-yl]-acetic acid methyl ester [4-(4-benzylsulfamoyl-phenyl)-6-fluoro-3-methyl-naphthalen-2-yl]-acetic acid methyl ester

📜在 Sodium Hydroxide,盐酸体系中,用 二氯甲烷,水 作为反应溶剂,化学反应 1.0H,反应生成 N-苄基-4-硼苯磺酰胺
参考文献:Halo Sulfonyl Aryl Boronates
标题:Halo Sulfonyl Aryl Boronates
摘要:本发明涉及一般式(i)的卤磺酰基芳基硼酸酯: 其中arylene表示一个含有1-3个环的碳环或杂环芳香环系统; R1,R2和r3分别为氢,C1-6烷基,C1-6烷氧基,卤素,硝基,氰基或苯基; X为氟,氯或溴;以及 Y是通过一条键连接到arylene上的硼氧杂环基,该环具有一个式为arylene(R1)(R2)(R3)So2X的基团,在硼氧杂环的另外两个硼原子上,或y是硼酸基团或硼酯基团. 该发明还涉及一般式(i)化合物的制备以及它们在有机合成中的应用.

专利信息

专利号:US-6872849-B2
优先权日:2002-11-08
标题 :Halo sulfonyl aryl boronates
发明人：VEDSO PER; OLESEN PREBEN HOULBERG; HOEG-JENSEN THOMAS
权利人:NOVO NORDISK AS
摘要:The present invention relates to halo sulfonyl aryl boronates of the general formula (I): n n wherein Arylene designates a carbocyclic or heterocyclic, aromatic ring system comprising 1-3 rings; R 1 , R 2 and R 3 are, independently, hydrogen, C 1-6 alkyl, C 1-6 alkoxy, halogen, nitro, cyano or phenyl; X is fluoro, chloro or bromo; and Y is a boroxine moiety attached via a bond from Arylene to one of the boron atoms of a boroxine ring which ring has a group of the formula -Arylene(R 1 )(R 2 )(R 3 )SO 2 X, wherein Arylene, R 1 , R 2 , R 3 and X are as defined above, at each of the other two boron atoms of the boroxine ring, or Y is a boronic acid group or a boronic ester group. The invention also relates to the preparation of the compounds of formula (I) and to their use in organic synthesis.

专利号:EP-1562961-B1
优先权日:2002-11-08
标 题 :Halo sulfonyl aryl boronates
发明人：VEDSO PER; OLESEN PREBEN HOULBERG; HOEG-JENSEN THOMAS
权利人:NOVO NORDISK AS
摘要:The present invention relates to halo sulfonyl aryl boronates of the general formula (I): wherein Arylene designates a carbocyclic or heterocyclic, aromatic ring system comprising 1-3 rings; R<1>, R<2> and R<3> are, independently, hydrogen, C1-6alkyl, C1-6alkoxy, halogen, nitro, cyano or phenyl;X is fluoro, chloro or bromo; and Y is a boroxine moiety attached via a bond from Arylene to one of the boron atoms of a boroxine ring which ring has a group of the formula -Arylene(R<1>)(R<2>)(R<3>)SO2X, wherein Arylene, R<1>, R<2>, R<3> and X are as defined above, at each of the other two boron atoms of the boroxine ring, or Y is a boronic acid group or a boronic ester group.The invention also relates to the preparation of the compounds of formula (I) and to their use in organic synthesis.