CAS: 5402-73-3; 2,5-Dichlorobenzenesulfonyl Chloride

上下游产品

CAS号106-46-7 1,4-二氯苯 | CAS号88-42-6 2,5-二氯苯磺酸二水合物 | CAS号7790-94-5 氯磺酸 | CAS号7664-93-9 硫酸 | CAS号34883-39-1 2,5-二氯联苯 | CAS号14295-43-3 颜料红88 | CAS号7790-94-5 氯磺酸 | CAS号7664-93-9 硫酸 | CAS号5858-18-4 2,5-二氯苯硫酚 | CAS号17733-24-3 2,5-DICHLOROTHI... | CAS号74832-74-9 4-(2,5-dichloro... | CAS号7720-45-8 2,5-二氯苯磺酰胺 | CAS号78150-04-6 methyl 2,5-dich... | CAS号6775-66-2 2,5-Dichloroben...

1,4-二氯苯置于氯磺酸体系中,用 1,2-二氯乙烷 作为反应溶剂,以80 %的收率获得产物2,5-二氯苄磺酸氯
参考文献:一种4'-氯-2-氨基联苯的合成方法
标题:一种4'-氯-2-氨基联苯的合成方法
摘要:本发明属于有机合成技术领域,具体涉及一种4'‑氯‑2‑氨基联苯的合成方法,具体步骤依次为:2,5‑二氯苯磺酰氯的合成,2,5‑二氯‑n‑苯苯磺酰胺的合成,2‑氯‑6H‑二苯并[c,E][1,2]噻嗪5,5‑二氧化物的合成,4'‑氯‑2‑氨基联苯的合成,该合成方法简单,无需使用贵金属催化剂,过渡金属,温和且绿色的反应后处理简便,无需进行复杂的操作,且所用原料基本均为廉价易得的基础化工原料,合成成本较低,收率高,非常适合工业化生产.

专利信息

专利号:US-5248793-A
优先权日:1990-10-17
标 题:Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate
发明人：MILLAR ALAN; BUTLER DONALD E
权利人:WARNER LAMBERT CO
摘要:An improved process for the preparation of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate is described where a hydroxy ester derivative is converted in two steps to the desired product, as well as valuable intermediates used in the process.

专利号:US-2010204463-A1
优先权日:2007-08-07
标题 :Preparation Of Synthetic Nucleosides via Pi-Allyl Transition Metal Complex Formation
发明人：LIOTTA DENNIS C; LI YONGFENG
权利人:LIOTTA DENNIS C; LI YONGFENG
摘要:This invention provides highly regioselective and stereoselective processes for preparing synthetic nucleosides. A process for the preparation of synthetic nucleosides is provided that comprises a) preparing a bicycloamide derivative, b) reacting the bicycloamide derivative with a nucleic acid base or heterocyclic base or salt thereof in the presence of a transition metal catalyst to form a cyclopentenecarboxamide, and c) cleaving a carboxamide group from the cyclopentenecarboxamide to form the synthetic nucleoside. The processes according to the invention can be used for the synthesis of a variety of anti-viral agents, including Abacavir, Carbovir, and Entecavir, as well as derivatives thereof.

专利号:US-5103024-A
优先权日:1990-10-17
标题:Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
发明人：MILLAR ALLAN; BUTLER DONALD E
权利人:WARNER LAMBERT CO
摘要:An improved process for the preparation of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate is described where a hydroxy ester derivative is converted in two steps to the desired product, as well as valuable intermediates used in the process.

专利号:US-2022363662-A1
优先权日:2021-04-20
标题 :Compounds as lxr agonists
发明人：PUJALA BRAHMAM; SATHE BALAJI DASHRATH; DANODIA ABHINANDAN; GUPTA ASHU; SONI SANJEEV; KUMAR VIVEK; ANSARI AMANTULLAH; KHAN FARHA; SARKAR ARINDAM; PAYGHAN PAVAN V
权利人:INTEGRAL BIOSCIENCES PRIVATED LTD
摘要:The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXRβ. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.

专利号:SK-280938-B6
优先权日:1990-10-17
标 题:METHOD OF SYNTHESIS OF (4R-CIS) -1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE AND INTERMEDIATE PRODUCTS

专利号:US-8034908-B2
优先权日:2003-02-14
标 题:Glycolipids and synthetic method thereof as well as their synthetic intermediates, and synthetic method thereof
发明人：ANNOURA HIROKAZU; MURATA KENJI; YAMAMURA TAKASHI
权利人:JAPAN GOVERNMENT
摘要:Novel glycolipid derivatives, where the substituent of the sphingosine base part is a short carbon chain alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group and efficient synthetic methods for practical mass production of the same and intermediates useful for the synthesis of these compounds. n Glycolipids having the formula (I): n nwhere R 3 indicates a substituted or unsubstituted C 1 to C 7 linear alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted aralkyl group and R 8 indicates a substituted or unsubstituted C 1 to C 35 alkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group are chemically synthesized.