CAS: 5146-66-7; 3,7-Dimethylocta-2,6-Dienenitrile

该化合物是一个清晰,无色的黄色液体,有新鲜的柑橘类味. 作为热兰醇的硝酸衍生物,它因其在碱性条件下的稳定性和耐氧化性而备受重视,使它在香味配方中成为首选,其低挥发性和长效芳香特征增强了其在香水中的用途,特别是植物和柑橘协定中的用途. 此外, Geranyl 硝酸盐与多种化妆品和个人护理成分的兼容性. 它的化学惰性和非敏性特性进一步增加了其在低过敏和高性能芳香应用中的适宜性.

结构式图片

相似化合物

5392-40-5 459-80-3 18794-84-8

欧盟法规

统一分类与标签REACH注册ECHA物质工作场所安全标识要求食品接触材料-禁用CMR物质化妆品禁用物质清单C&L通报ECHA物质REACH预注册废弃物危险特性清单

上下游产品

3,7-dimethyl°Cta-2,6-dienal oxime 6-Methyl-hept-5-en-2-on cyanoacetic acid (E/Z)-3,7-dimethyl-2,6-°Ctadienal (1,5-Dimethyl-hex-4-enylidene)-cyclohexane citronellylnitrile 2,2,6-trimethyl-1-cyclohexenylcarbonitrile 2,6,6-trimethyl-2-cyclohexenecarbonitrile

合成工艺路线路线简述

    📜柠檬醛置于copper(L) Chloride Ammonium Hydroxide,双氧水体系中,用 异丙醇 作为反应溶剂,以87%的收率获得产物3,7-二甲基-2,6-辛二烯腈
    参考文献:利用氨和过氧化氢将醛转化为腈的一种有效的新方法
    标题:利用氨和过氧化氢将醛转化为腈的一种有效的新方法
    摘要:在温和的条件下,在铜盐或络合物的存在下,通过与氨和过氧化氢水溶液的均相反应,将醛转化为相应的腈.
    DOI:10.1016/s0040-4039(00)01168-0

    海关参考信息

    专利信息


    专利号:US-5514830-A
    优先权日:1991-07-25
    标题 :Process for producing nitrile
    发明人:OKU MASAYUKI; FUJIKURA YOSHIAKI
    权利人:KAO CORP
    摘要:The present invention provides a process for producing a nitrile represented by the general formula (1): RC=N(1) wherein R is alkyl, alkenyl, aralkyl or aryl, each may have a substituent, characterized by heating an aldoxime represented by the general formula (2): RCH=NOH(2) wherein R is as defined above, in the presence of one or more catalysts selected from hydroxides of alkali metals, alcoholates of alkali metals, hydroxides of alkaline earth metals and alcoholates of alkaline earth metals, and distilling off water formed in the course of the reaction from the reaction system. The process according to the present invention can produce a nitrile which is useful as a perfume or as a starting material for the organic synthesis of perfumes, medicines and so on in high yields and advantageously from the viewpoint of production economy.

    专利号:US-12076423-B2
    优先权日:2015-12-23
    标题 :Spiculisporic acid-based composition
    发明人:AGNAOU REDA; MARION CATHERINE
    权利人:OREAL
    摘要:Composition in the form of an oil-in-water emulsion that includes at least 1% of an oil phase, and an aqueous phase. The composition includes 0.1 to 15 wt % spiculisporic acid relative to the total weight of the composition, at least one base selected from amino acids and alkanolamines in an amount suitable for forming at least a monosalt of spiculisporic acid, less than 3% glycol(s) and/or polyol(s) relative to the total weight of the composition, at least one UV filter and/or an additive selected from volatile aromatic materials such as essential oils and fragrance substances, fillers, dyeing materials such as pigments, mother-of-pearl or particles with a metallic sheen, moisturizers, anti-wrinkle or anti-age agents, peeling agents, antioxidants, active ingredients stimulating the synthesis of epidermal and/or dermal macromolecules, dermo-relaxing agents, depigmentation agents, deodorant agents and mixtures thereof.

    专利号:EP-0550762-B1
    优先权日:1991-07-25
    标 题 :Process for producing nitrile
    发明人:OKU MASAYUKI; FUJIKURA YOSHIAKI
    权利人:KAO CORP
    摘要:A process for producing a nitrile represented by the general formula (1): RC = N wherein R represents alkyl, alkenyl, aralkyl or aryl each of which may be substituted, by heating an aldoxime represented by the general formula (2): RCH = NOH wherein R is as defined above, in the presence of at least one catalyst selected among hydroxides and alcoholates of alkali metals and alkaline earth metals, and distilling off water formed in the course of the reaction from the reaction system. The process enables nitriles useful as the starting material for the organic synthesis of perfumes, medicines and so forth to be produced in high yields at a remarkably reduced production cost.

    专利号:US-8349790-B2
    优先权日:2007-10-29
    标 题:Substituted octane(ene) nitriles, methods for the synthesis thereof and uses thereof in perfumery
    发明人:MANE JEAN; CLINET JEAN-CLAUDE
    权利人:MANE FILS V; MANE JEAN; CLINET JEAN-CLAUDE
    摘要:Compounds of general formula (I) below: in which R is a hydrogen atom, a methyl group, a CH2OH group, an ester group, preferably COOEt, or a methylene group, and in which not more than one of the four dashed lines represents a carbon-carbon double bond, and also their enantiomers and their diastereoisomers, a process for preparing them, and their use as an odorant agent in perfuming compositions.

    专利号:EP-2840077-A1
    优先权日:2013-08-20
    标 题:Process for the manufacture of hydrogenated nitriles
    发明人:BEUMER RAPHAEL; BONRATH WERNER; LEHMANN HAJO; MEDLOCK JONATHAN ALAN
    权利人:DSM IP ASSETS BV
    摘要:The present invention relates to the manufacture and the use of specific organic compounds of formula (II)n nwherein n is either 1 or 2, and wherein R 1 is linear C 1-4 alkyl or branched C 3-4 alkyl, wherein R 2 is hydrogen or linear C 1-4 alkyl or branched C 3-4 alkyl, as aroma ingredients in flavors and fragrances. Furthermore the invention relates to new specific organic compounds and their synthesis, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.

    专利号:BE-866404-A
    优先权日:1977-04-26
    标题:PROCESS FOR THE SYNTHESIS OF DINITRILS, PRODUCTS THUS OBTAINED AND THEIR DERIVATIVES

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: S Chen, Et Al. Blocking Adenylyl Cyclase Inhibits Olfactory Generator Currents Induced By "Ip(3)-Odors". J Neurophysiol. 2000 Jul;84(1):575-80.

    合成参考文献


    摘要:Dornan, L. M.; Hughes, N. L.; Muldoon, M. J., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 549.
    摘要:Food and Cosmetics Toxicology., 14(787), 1976
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