CAS: 38302-15-7; (S)-5,7-Dimethoxy-2-(4-Methoxyphenyl)Chroman-4-One

上下游产品

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on dimethyl sulfate diiodomethane 2'-hydroxy-4,4',6'-trimethoxychalcone5,7,4'-O,O,O-trimethoxy-8-methylnaringenin 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on 8-chloro-5,7,4'-trimethoxyflavanone

专利信息

专利号:US-7638554-B2
优先权日:2002-04-18
标题 :Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
发明人：WALEH NAHID; ZAVERI NURULAIN T
权利人:STANFORD RES INST INT
摘要:Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) n nwherein R 1 through R 3 and R 5 through R 11 are defined herein, and α, β and γ are optional bonds, providing that when α is absent, β is present, and when β is absent, α is present. When α is present, preferred R 4 moieties are selected from O, S, NH and CH 2 , and when α is absent, preferred R 4 groups are selected from OH, SH, NH 2 and CH 3 . When γ is present, the preferred R 5 substituent is O, while when γ is absent, the preferred R 5 substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.

专利号:US-7329687-B2
优先权日:2002-04-18
标 题:Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents
发明人：ZAVERI NURULAIN; CHAO WAN-RU
权利人:STANFORD RES INST INT
摘要:Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) n nwherein R 1 through R 3 and R 5 through R 11 are defined herein, and α, β, and γ are optional bonds, providing that when α is absent, β is present, and when β is absent, α is present. When α is present, preferred R 4 moieties are selected from O, S, NH and CH 2 , and when α is absent, preferred R 4 groups are selected from OH, SH, NH 2 and CH 3 . When γ is present, the preferred R 5 substituent is O, while when γ is absent, the preferred R 5 substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.