CAS: 27994-11-2; Cimigenoside

该化合物是一种以其结构为特征的甘蓝表面化合物,由与-D-Xyl-pyrnoside单元相连的西米格努尔合成物组成,该化合物来自西米格努尔,该天然产品以其潜在的生物活动为名,包括抗氧化剂和抗炎特性.Cimipgenol-3-O-D-xyl-xyl-pylranoside的甘油混合物的粘合物加强了其在水中的溶性,而该化合物的对口体则可能会影响其生物利用率和药理效应.Xylpranoside装置的存在表明,该化合物可能与各种生物系统发生相互作用,有可能影响代谢途径.此外,该化合物的结构特征可能会在不同条件下促进其稳定性和再活性.正在对辛米格gen醇-3-O-D-D-xyl-sylmerantherside进行研究,并有兴趣在药品和营养学应用中,特别是在天然产品化学和植物来源衍生的治疗剂方面.

结构式图片

上下游产品

CAS号1316305-70-0 2'-O-acetylcimi... | CAS号87-72-9 L-阿拉伯糖

合成工艺路线路线简述

    📜2'-O-Acetylcimigenol-3-O-β-D-Xylopyranoside置于potassium Carbonate体系中,用 甲醇 用作溶剂,化学反应生成升麻环氧醇苷
    参考文献:来自 Cimicifuga Foetida Linnaeus 地上部分的环烷烃三萜类化合物
    标题:来自 Cimicifuga Foetida Linnaeus 地上部分的环烷烃三萜类化合物
    摘要:Cycloartane 三萜,2',24-O-Diacetylisodahurinol-3-O-α-L-Arabinopyranoside,24-O-Acetylisodahurinol-3-O-α-L-Arabinopyranoside,12β-Hydroxy-25-Anhydrocimigenol,Cimigenol-12-一,12β-羟基-15-脱氧香茅醇,2'-O-乙酰基-24-Epi-Cimigenol-3-O-α-L-阿拉伯吡喃糖苷,2'-O-乙酰基香茅醇-3-O-β-D-吡喃木糖苷,25-Anhydrocimigenol-3-O-α-L-Arabinopyranoside,2',23-O-Diacetylshengmanol-3-O-α-L-Arabinopyranoside,和 2',24-O-Diacetyl-25-Anhydroshengmanol-3-O-α-
    Doi:10.1016/j.Phytochem.2011.03.022

    海关参考信息

    专利信息


    专利号:US-8263755-B2
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production
    发明人:FINDEIS MARK A
    权利人:FINDEIS MARK A; SATORI PHARMACEUTICALS INC
    摘要:As described herein, the present invention provides methods for preparing compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.

    专利号:US-2013059804-A1
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:EP-2073638-A2
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:EP-2073638-B1
    优先权日:2006-11-20
    标 题 :Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:WO-2008136863-A2
    优先权日:2006-11-20
    标题 :Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:US-2010197615-A1
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1177/1934578x0800300925
    摘要:Jiang B, Reynertson KA, Keller AC, Einbond LS, Bemis DL, Weinstein IB, Kronenberg F, Kennelly EJ. Extraction Methods Play a Critical Role in Chemical Profile and Biological Activities of Black Cohosh. Natural Product Communications. 2008 Sep;3(9). doi: 10.1177/1934578x0800300925.
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