CAS: 221679-84-1; 4-Chloro-6-Ethoxy-2-(Methylthio)Pyrimidine

该化合物是替代的微米丁衍生物,在有机合成和制药中间体中具有显著用途,其结构特征是4级氯化物组,6级乙氧替代物组和2级甲基硫化物组,使其成为进一步功能化的多功能构件. 化合物的反作用性,特别是在4-氯场地,允许选择性的核分裂生物替代反应,促进更复杂的七环环系统合成. 它在标准条件下的稳定性和定义明确的再活动特征增强了其在医药化学和农业化学研究中的适宜性. 这一化合物因其在开发生物活性分子方面的作用而特别受到重视.

英文名称4-Chloro-6-Ethoxy-2-(Methylthio)Pyrimidine
中文名称4-氯-6-乙氧基-2-甲硫基嘧啶
IUPAC名称4-chloro-6-ethoxy-2-(methylthio)pyrimidine
其它别名4-氯-6-乙氧基-2-甲硫基嘧啶; 2-甲硫基-4-乙氧基-6-氯嘧啶 250Mg; 4-Chloro-6-Ethoxy-2-Methylsulfanyl-Pyrimidine
CAS编号221679-84-1
MFCD编号:MFCD00672143
分子式:C7H9ClN2OS分子量:204.68
产品CID: 1148402
产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物

相似结构搜索
InChIKey: UGHUXTAMHJKMPX-UHFFFAOYSA-N
InChI=1S/C7H9ClN2OS/c1-3-11-6-4-5(8)9-7(10-6)12-2/h4H,3H2,1-2H3
计算化学: 氢键受体数4.0氢键供体数0.0可旋转键数3.0

相似化合物

89466-42-2 1289386-28-2 6632-63-9

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

合成工艺路线路线简述

📜4,6-二氯-二甲硫基嘧啶,Sodium Ethanolate 以乙醇用作溶剂,化学反应生成4-氯-6-乙氧基-2-甲硫基嘧啶
参考文献:Compounds And Pharmaceutical Compositions That Degrade Swi/snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A
标题:Compounds And Pharmaceutical Compositions That Degrade Swi/snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A
摘要:Disclosed Are Compounds Of Formula I,Or A Pharmaceutically Acceptable Salt,Solvate,Stereoisomer,Or Tautomer Thereof,That Are Useful For Modulating Or Degrading Protein Which Is Expressed From One Or More Swi/snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A (Smarca) (E.G.,Smarca2 And/or Smarca4). (I)