CAS: 207591-86-4; (S)-2-Amino-3-(4-Nitrophenyl)Propanoic Acid Hydrate

相似化合物

949-99-5 444777-67-7 95753-55-2

专利信息

专利号:US-12077484-B2
优先权日:2019-12-23
标 题 :Process for the synthesis of melphalan
发明人：ALLEGRINI PIETRO; BONETTI ANDREA; MOLINARI MARCO; GAMBINI ANDREA
权利人:INDENA SPA
摘要:The invention relates to a process for the preparation of Melphalan (4-[bis(2-chloroethyl)amino]-L-phenylalanine of formula (I)said process comprising the reaction of a 4-amino-L-phenylalanine protected at the carboxy and amino aminoacidic groups with an agent able to convert the aromatic amino group into a group of formula: —N(CH2CH2OS(O)nO−)2, wherein n is 1 or 2 followed by conversion of the —N(CH2CH2OS(O)nO−)2 group into a —N(CH2CH2Cl)2 group.The invention also provides novel intermediates useful for the preparation of Melphalan.

专利号:US-2023286901-A1
优先权日:2019-12-23
标题:Process for the synthesis of melphalan

专利号:WO-2025125353-A1
优先权日:2023-12-13
标题:Method of preparation of zavegepant, synthesis intermediates of zavegepant and methods of preparation thereof
发明人：SÃ?NCHEZ CASALS CARLES; FAZIO ZALÃ?NYI ZENO; BALLETTE ROBERTO
权利人:MOEHS IBERICA SL
摘要:The present invention relates to a method of preparation of zavegepant and to reaction intermediates useful in the preparation of zavegepant, to a method of preparation of said intermediates, and to the use of said intermediates in the preparation of zavegepant.

专利号:EP-4081503-B1
优先权日:2019-12-23
标题:A process for the synthesis of melphalan

专利号:US-2023094970-A1
优先权日:2019-12-23
标题 :A process for the synthesis of melphalan

专利号:US-11787761-B2
优先权日:2019-12-23
标 题 :Process for the synthesis of Melphalan