CAS: 18540-29-9; Chromium(6+)

专利信息

专利号:US-2024294462-A1
优先权日:2023-02-15
标题:Method for the Synthesis of Ionizable Lipids Using a Doubly Alkylated Intermediate
发明人：SAADATI FARIBA; TRAN HUY; CIUFOLINI MARCO; ATMURI N D PRASAD
权利人:NANOVATION THERAPEUTICS INC
摘要:Provided herein is a method for the preparation of ionizable, cationic amino lipids using a doubly alkylated nucleophilic intermediate to produce a ketone. The ketone, or a corresponding alcohol, is subjected to one or more synthesis steps to add an ionizable moiety thereto. The method can be advantageously employed for the synthesis of unsymmetrical analogues of the above lipids that would be considerably more difficult to make by alternative strategies. The method can also be used to prepare symmetrical ionizable, cationic amino lipids with fewer steps and/or with the use of fewer hazardous chemicals than known synthesis methods.

专利号:US-9422326-B2
优先权日:2012-09-04
标 题:Process for preparing 11-methylene-18-methyl-estr-4-en-3, 17-dione, useful as intermediate compound for the synthesis of molecules having pharmacological activity
发明人：LENNA ROBERTO; MARIANI EDOARDO; VANOSSI ANDREA
权利人:IND CHIMICA SRL
摘要:There is described a process for the industrial synthesis of 11-methylene-18-methyl-estr-4-en-3,17-dione, a compound having the structure formula (I) depicted below: (Formula I) (I) useful as intermediate compound in the synthesis of the progestin compounds Desogestrel and Etonogestrel.

专利号:US-7405313-B2
优先权日:2006-09-13
标题:Method for the synthesis of basic chromium carboxylates
发明人：VINCENT JOHN B
权利人:UNIV ALABAMA
摘要:A method for the synthesis of a chromium complex 2, [Cr 3 O(carboxylate) 6 (H 2 O) 3 ] + (2), wherein carboxylate is a substituted or unsubstituted C2-C5 alkyl carboxylate, is provided, including the step of: n heating an aqueous reaction mixture of a Cr(III) salt, a substituted or unsubstituted C2-C5 alkyl carboxylic acid and a metal hydroxide for a time period and at a temperature sufficient to generate an aqueous product mixture comprising chromium complex 2 and non-toxic byproducts.

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-4084936-A
优先权日:1975-08-16
标 题 :Reducing corrosion in reactors used for the synthesis of chromium dioxide
发明人：OHLINGER MANFRED; WAGNER GERHARD; HONECKER GERHARD; STRITZINGER HEINZ; SPAEHN HEINZ
权利人:BASF AG
摘要:In order to reduce corrosion of the inside walls of a reactor made of iron or an iron alloy and used for the synthesis of chromium dioxide by hydrothermal conversion of chromium(VI) oxide with chromium oxides of lower valency, lead or bismuth is added at those points of the reactor at which an aqueous phase occurs during conversion and which do not contact the chromium oxides to be converted. The lead or bismuth may be used in metallic form or in the form of their oxides, hydroxides or salts.

专利号:US-4107089-A
优先权日:1977-03-14
标 题 :Catalyst for the synthesis of methanol and method for preparing same
发明人：BONDAR PETR GRIGORIEVICH; GOROSHKO OLEG NIKOLAEVICH; SUSCHAYA LARISA EMMANUILOVNA; LAVROVA VALENTINA VASILIEVNA; LELEKA VALENTINA EMMANUILOVNA; ILKO EDUARD GRIGORIEVICH
权利人:BONDAR PETR GRIGORIEVICH; GOROSHKO OLEG NIKOLAEVICH; SUSCHAYA LARISA EMMANUILOVNA; LAVROVA VALENTINA VASILIEVNA; LELEKA VALENTINA EMMANUILOVNA; ILKO EDUARD GRIGORIEVICH
摘要:A catalyst for the synthesis of methanol which contains an oxide of one or more metals of Group VI, chromium subgroup, of the periodic system, copper oxide, zinc oxide and an oxide of one or more hardly reducible metals of Group II-III of the periodic system.