CAS: 17484-36-5; 4-Methyl-3-Nitroanisole

该化合物是一种有机化合物,属于硝基替代芳香化合物类别,其特征为:甲氧基组(-OCH3)和硝基组(-NO2),附于一个苯环,有助于其化学反应和物理特性;该化合物一般是黄色的,呈褐色的固体,具有芳香性质,具有稳定性和独特的电子特性;硝基化合物组的存在使其有可能成为电子替代反应的候选物,而甲氧基组可能影响该化合物的溶性与再活性. 4-甲基-1-甲基-2-硝基苯在有机合成中经常使用,并可作为各种药品和农用化学品生产的中间体.在处理该化合物时,应注意安全防范措施,因为硝基化合物可能构成危险,并可能构成环境风险.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号2042-14-0 4-甲基-3-硝基苯酚 | CAS号77-78-1 硫酸二甲酯 | CAS号74-88-4 碘甲烷 | CAS号5344-78-5 4-溴-3-硝基苯甲醚 | CAS号544-97-8 二甲基锌 | CAS号106-44-5 对甲酚 | CAS号134-19-0 2-甲氧基-4-硝基-5-甲基苯胺 | CAS号621-02-3 Carbonic acid,b... | CAS号106-49-0 对甲苯胺 | CAS号186581-53-3 重氮甲烷 | CAS号4294-95-5 2-氨基-4-甲氧基苯甲酸 | CAS号3189-13-7 6-甲氧基吲哚 | CAS号50868-72-9 5-甲氧基-2-甲基苯胺 | CAS号22996-23-2 4-甲氧基-2-硝基苄醇 | CAS号20734-74-1 5-甲氧基-2-甲基苯酚 | CAS号2400-35-3 ethyl 6-methoxy... | CAS号33844-21-2 4-甲氧基-2-硝基苯甲酸 | CAS号57559-52-1 1-(溴甲基)-4-甲氧基-2-硝基苯 | CAS号22996-21-0 4-甲氧基-2-硝基-苯甲醛 | CAS号223787-57-3 N-[2-[2-(2-brom...

合成工艺路线路线简述

    2-甲氧基-4-硝基-5-甲基苯胺 反应生成4-甲基-3-硝基苯甲醚
    参考文献:2-氨基酪氨酸,酪氨酸的类似物.
    标题:2-氨基酪氨酸,酪氨酸的类似物.
    摘要:
    Doi:10.1021/jm00324A008

    海关参考信息

    专利信息


    专利号:US-9795685-B2
    优先权日:2012-08-21
    标 题 :Haptens of aripiprazole
    发明人:LIN RONGHUI; SALTER RHYS; DECORY THOMAS R; HRYHORENKO ERIC; REMMERIE BART M; SANKARAN BANUMATHI
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The invention relates to compounds of Formula I, wherein R 1 , R 2 , and R 3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.

    专利号:US-2010075297-A1
    优先权日:2006-12-20
    标题 :Photosensitive polypeptide and methods of their production and use
    发明人:LAWRENCE DAVID S
    权利人:LAWRENCE DAVID S
    摘要:Methods for producing polypeptides caged with a photolabile group on one or more backbone nitrogens are provided, in which the photolabile group is added to a growing polypeptide chain during polypeptide synthesis. Photosensitive polypeptides produced by the methods are described, as are methods of using such photosensitive polypeptides to assay enzyme activity or inhibit protein-protein interactions. Methods for producing polypeptides caged with a photolabile group on one or more side chain nitrogens, where the photolabile group is incorporated into the side chain during polypeptide synthesis, are also provided.

    专利号:US-8969535-B2
    优先权日:2006-12-05
    标 题:Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing
    发明人:WU WEIDONG; LITOSH VLADISLAV A; STUPI BRIAN P; METZKER MICHAEL L
    权利人:WU WEIDONG; LITOSH VLADISLAV A; STUPI BRIAN P; METZKER MICHAEL L; LASERGEN INC
    摘要:Provided are novel nucleotides, nucleoside, and their derivatives described herein, that can be used in DNA sequencing technology and other types of DNA analysis. In one embodiment, the nucleotide or nucleoside with an unprotected 3′-OH group is derivatized at the nucleobase to include a fluorescent dye attached via a linker to a photocleavable terminating group. The photocleavable-fluorescent group is designed to terminate DNA synthesis as well as be cleaved so that DNA oligomers can be sequenced efficiently in a parallel format. The design of such rapidly cleavable fluorescent groups on nucleotides and nucleosides can enhance the speed and accuracy of sequencing of large oligomers of DNA in parallel, to allow rapid whole genome sequencing, and the identification of polymorphisms and other valuable genetic information, as well as allowing further manipulation and analysis of nucleic acid molecules in their native state following cleavage of the fluorescent group.

    专利号:US-2025101038-A1
    优先权日:2021-12-24
    标 题 :Compounds
    发明人:BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG
    权利人:Psylo Pty Ltd
    摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
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    主要参考文献

    [参考文献]: P Wentworth Jr, Et Al. A Bait And Switch Hapten Strategy Generates Catalytic Antibodies For Phosphodiester Hydrolysis. Proc Natl Acad Sci U S A. 1998 May 26;95(11):5971-5.

    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 108.
    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 89.
    摘要:Molander, G. A.; Ryu, D., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 2, 45.
    参考文献:10.1097/01.mnm.0000126629.09543.1d
    摘要:Lee SY, Choe YS, Kim YR, Paik JY, Choi BW, Kim SE, Lee KH, Choi Y, Kim BT. Synthesis and evaluation of 5,7-dihydro-3-[2-[1-(4-[18F]-fluorobenzyl)-4-piperidinyl]ethyl]-6H-pyrrolo[3,2-f]-1,2-benzisoxazol-6-one for in vivo mapping of acetylcholinesterase. Nucl Med Commun. 2004 Jun;25(6):591–6. doi: 10.1097/01.mnm.0000126629.09543.1d.
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