1,2,4-三甲基苯置于manganese(Iv) Oxide,硫酸体系中,化学反应生成2,4-二甲基苯甲醛 参考文献:Law,Journal Of The Chemical Society,1907,Vol. 91,P. 759 标题:Law,Journal Of The Chemical Society,1907,Vol. 91,P. 759
专利号:US-8742028-B2 优先权日:2009-05-06 标 题:Solid support for Fmoc-solid phase synthesis of peptide acids 发明人:SRIVASTAVA KRIPA S; DAVIS MATTHEW R 权利人:SRIVASTAVA KRIPA S; DAVIS MATTHEW R; MALLINCKRODT LLC 摘要:The present invention provides a solid support for Fmoc-solid phase synthesis of peptides. In particular, the solid supports of the invention may be utilized to produce peptide acids.
专利号:US-6384228-B2 优先权日:1998-05-26 标题 :Method for synthesis of halopyridyl-azacyclopentane derivative and intermediate thereof 发明人:NODE MANABU; NAKAMURA DAISAKU; FUJIWARA TOSHIO; ICHIHASHI SHOGO 权利人:NIHON MEDIPHYSICS CO LTD 摘要:The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.
专利号:US-8729277-B2 优先权日:2009-04-06 标 题:Processes for the synthesis of gamma nitrocarbonyl and gamma dicarbonyl compounds and their pyrrole derivatives 发明人:YANG HU; BARALT EDUARDO J 权利人:YANG HU; BARALT EDUARDO J; CHEVRON PHILLIPS CHEMICAL CO 摘要:The present invention discloses processes for producing γ-nitrocarbonyl and γ-dicarbonyl compounds, which can be precursors in the synthesis of pyrrole compounds. A process for producing pyrroles such as 2,5-dimethylpyrrole, and structurally similar pyrrole compounds, is also disclosed.
专利号:US-2009048451-A1 优先权日:2007-08-16 标题 :Synthesis of triazole derivatives from Lewis base mediated nitroalkene-aldehyde coupling 发明人:SHI XIAODONG 权利人:UNIV WEST VIRGINIA 摘要:In the present invention a method to synthesize a triazole derivative from a Lewis base mediated nitroalkene-aldehyde coupling is revealed. In this synthesis a nitroalkene is reacted with an aromatic aldehyde in the presence of a Lewis Base, NaN 3 , and a solvent for about 2 hours to about 48 hours at ambient conditions such as room temperature. The synthesized product may be any type of 4,5 disubstituted-1,2,3-triazoles. Of the nitroalkenes alkenes most β-alkyl nitroalkenes can react such as a β-substituted alkene. The aromatic aldehyde can be any 6 carbon aromatic aldehyde whether unsubstituted, substituted, disubstituted, heterocyclic, or a five carbon thiophene carboxaldehyde. The reaction takes place in the presence of NaN 3 , a Lewis base, and solvents.
专利号:US-8202985-B2 优先权日:2005-10-31 标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection 发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H 权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO 摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.
专利号:US-7759471-B2 优先权日:2005-10-31 标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection 发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H 权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO 摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.
[参考文献]: Matthias Onghena, Et Al. Development And Application Of A Non-Targeted Extraction Method For The Analysis Of Migrating Compounds From Plastic Baby Bottles By Gc-Ms. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(12):2090-102.
合成参考文献
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