CAS: 76839-21-9; 1-(4-Phenoxyphenyl)Thiourea

化学文摘社编号为76839-21-9,是一个独特的识别标志,便于搜索有关其特性,安全数据和监管状况的信息.与任何化学物质一样,在实验室环境中与4-苯基苯基尿进行工作时,适当的处理和安全防范是不可或缺的.

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上下游产品

CAS号76838-41-0 N-{[(4-phenoxyp... | CAS号139-59-3 4-氨基二苯醚 | CAS号333-20-0 硫氰酸钾 | CAS号3529-87-1 4-苯氧基苯基异硫氰酸酯 | CAS号73166-61-7 4-phenoxyanilin...

合成工艺路线路线简述

  • 合成目标产物 4-Phenoxyphenylthiourea 主要起始原料 N-{[(4-Phenoxyphenyl)Amino]Carbonothioyl}Benzamide
  • (文献来源)合成步骤主要原料 N-{[(4-Phenoxyphenyl)Amino]Carbonothioyl}Benzamide
📜4-苯氧苯基异硫氰酸盐置于氨体系中,用 甲醇 作为反应溶剂,化学反应 12.0H,反应生成 4-苯氧基苯基硫脲
参考文献:Synthesis Of Thiophene-2-Carboxamidines Containing 2-Amino-Thiazoles And Their Biological Evaluation As Urokinase Inhibitors
标题:Synthesis Of Thiophene-2-Carboxamidines Containing 2-Amino-Thiazoles And Their Biological Evaluation As Urokinase Inhibitors
摘要:The Serine Protease Urokinase (Upa) Has Been Implicated In The Progression Of Both Breast And Prostate Cancer. Utilizing Structure Based Design,The Synthesis Of A Series Of Substituted 4-[2-Amino-1,3-Thiazolyl]-Thiophene-2-Carboxamidine Is Described. Further Optimization Of This Series By Substitution Of The Terminal Amine Yielded Urokinase Inhibitors With Excellent Activities. (C) 2001 Elsevier Science Ltd. All Rights Reserved.
DOI:10.1016/s0960-894X(01)00102-0

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专利信息


专利号:CN-106674128-A
优先权日:2016-12-31
标题 :A class of licochalcone A thiouracil derivatives with anti-tumor activity and its synthesis method

专利号:CN-107235916-A
优先权日:2016-12-31
标题:A kind of licochalcone A thiouracil derivative with antitumor activity and its synthesis method

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合成参考文献

参考DOI号:10.1248/cpb.33.4409
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